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TMEFF1 is a neuron-specific restriction factor for herpes simplex virus.
Dai Y, Idorn M, Serrero MC, Pan X, Thomsen EA, Narita R, Maimaitili M, Qian X, Iversen MB, Reinert LS, Flygaard RK, Chen M, Ding X, Zhang BC, Carter-Timofte ME, Lu Q, Jiang Z, Zhong Y, Zhang S, Da L, Zhu J, Denham M, Nissen P, Mogensen TH, Mikkelsen JG, Zhang SY, Casanova JL, Cai Y, Paludan SR. Dai Y, et al. Among authors: reinert ls. Nature. 2024 Aug;632(8024):383-389. doi: 10.1038/s41586-024-07670-z. Epub 2024 Jul 24. Nature. 2024. PMID: 39048823
Functional IRF3 deficiency in a patient with herpes simplex encephalitis.
Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH. Andersen LL, et al. Among authors: reinert ls. J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27. J Exp Med. 2015. PMID: 26216125 Free PMC article.
STEEP mediates STING ER exit and activation of signaling.
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R, Hartmann R, Chen ZJ, Enghild JJ, Bak RO, Thomsen MK, Paludan SR. Zhang BC, et al. Among authors: reinert ls. Nat Immunol. 2020 Aug;21(8):868-879. doi: 10.1038/s41590-020-0730-5. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690950 Free PMC article.
The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation.
Farahani E, Reinert LS, Narita R, Serrero MC, Skouboe MK, van der Horst D, Assil S, Zhang B, Iversen MB, Gutierrez E, Hazrati H, Johannsen M, Olagnier D, Kunze R, Denham M, Mogensen TH, Lappe M, Paludan SR. Farahani E, et al. Among authors: reinert ls. Cell Rep. 2024 Feb 27;43(2):113792. doi: 10.1016/j.celrep.2024.113792. Epub 2024 Feb 15. Cell Rep. 2024. PMID: 38363679 Free PMC article.
46 results