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Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2.
Chen S, Wang Q, Bakker D, Hu X, Zhang L, van der Made I, Tebbens AM, Kovácsházi C, Giricz Z, Brenner GB, Ferdinandy P, Schaart G, Gemmink A, Hesselink MKC, Rivaud MR, Pieper MP, Hollmann MW, Weber NC, Balligand JL, Creemers EE, Coronel R, Zuurbier CJ. Chen S, et al. Among authors: schaart g. Basic Res Cardiol. 2024 Oct;119(5):751-772. doi: 10.1007/s00395-024-01067-9. Epub 2024 Jul 24. Basic Res Cardiol. 2024. PMID: 39046464 Free PMC article.
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM. Wu J, et al. Among authors: schaart g. Cell. 2012 Jul 20;150(2):366-76. doi: 10.1016/j.cell.2012.05.016. Epub 2012 Jul 12. Cell. 2012. PMID: 22796012 Free PMC article.
144 results