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Allosteric nanobodies to study the interactions between SOS1 and RAS.
Fischer B, Uchański T, Sheryazdanova A, Gonzalez S, Volkov AN, Brosens E, Zögg T, Kalichuk V, Ballet S, Versées W, Sablina AA, Pardon E, Wohlkönig A, Steyaert J. Fischer B, et al. Nat Commun. 2024 Jul 23;15(1):6214. doi: 10.1038/s41467-024-50349-2. Nat Commun. 2024. PMID: 39043660 Free PMC article.
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Uchański T, Masiulis S, Fischer B, Kalichuk V, López-Sánchez U, Zarkadas E, Weckener M, Sente A, Ward P, Wohlkönig A, Zögg T, Remaut H, Naismith JH, Nury H, Vranken W, Aricescu AR, Pardon E, Steyaert J. Uchański T, et al. Among authors: fischer b. Nat Methods. 2021 Jan;18(1):60-68. doi: 10.1038/s41592-020-01001-6. Epub 2021 Jan 6. Nat Methods. 2021. PMID: 33408403 Free PMC article.
Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras.
Peeters K, Van Leemputte F, Fischer B, Bonini BM, Quezada H, Tsytlonok M, Haesen D, Vanthienen W, Bernardes N, Gonzalez-Blas CB, Janssens V, Tompa P, Versées W, Thevelein JM. Peeters K, et al. Among authors: fischer b. Nat Commun. 2017 Oct 13;8(1):922. doi: 10.1038/s41467-017-01019-z. Nat Commun. 2017. PMID: 29030545 Free PMC article.
Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Van Holsbeeck K, Fischer B, Gonzalez S, Gadais C, Versées W, Martins JC, Martin C, Wohlkönig A, Steyaert J, Ballet S. Van Holsbeeck K, et al. Among authors: fischer b. Angew Chem Int Ed Engl. 2023 Jun 12;62(24):e202219095. doi: 10.1002/anie.202219095. Epub 2023 May 5. Angew Chem Int Ed Engl. 2023. PMID: 37067463
Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).
Stein MJ, Weber A, Bamberg F, Baurecht H, Berger K, Bohmann P, Brenner H, Brummer J, Dörr M, Fischer B, Gastell S, Greiser KH, Harth V, Hebestreit A, Heise JK, Herbolsheimer F, Ittermann T, Karch A, Keil T, Kluttig A, Krist L, Michels KB, Mikolajczyk R, Nauck M, Nimptsch K, Obi N, Pischon T, Pivovarova-Ramich O, Schikowski T, Schmidt B, Schulze MB, Steindorf K, Zylla S, Leitzmann MF. Stein MJ, et al. Among authors: fischer b. Int J Obes (Lond). 2025 Jan 24. doi: 10.1038/s41366-025-01721-9. Online ahead of print. Int J Obes (Lond). 2025. PMID: 39856244
2,141 results