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The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Lim JJ, Jones CM, Loh TJ, Ting YT, Zareie P, Loh KL, Felix NJ, Suri A, McKinnon M, Stevenaert F, Sharma RK, Klareskog L, Malmström V, Baker DG, Purcell AW, Reid HH, La Gruta NL, Rossjohn J. Lim JJ, et al. Among authors: loh tj, loh kl. Sci Immunol. 2021 Apr 16;6(58):eabe0896. doi: 10.1126/sciimmunol.abe0896. Sci Immunol. 2021. PMID: 33863750
GATA4 downregulation enhances CCL20-mediated immunosuppression in hepatocellular carcinoma.
Nasir NJM, Chuah S, Shuen T, Prawira A, Ba R, Lim MC, Chua J, Nguyen PHD, Lim CJ, Wasser M, Hazirah SN, Lim TKH, Leow WQ, Loh TJ, Wan WK, Pang YH, Soon G, Cheow PC, Kam JH, Iyer S, Kow A, Dan YY, Bonney GK, Chung A, Goh BKP, Chow PKH, Albani S, Zhai W, Ouyang JF, Toh HC, Chew V. Nasir NJM, et al. Among authors: loh tj. Hepatol Commun. 2024 Aug 19;8(9):e0508. doi: 10.1097/HC9.0000000000000508. eCollection 2024 Sep 1. Hepatol Commun. 2024. PMID: 39167427 Free PMC article.
A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and 'bad apple' effect on clinical trajectory.
Chen J, Kaya NA, Zhang Y, Kendarsari RI, Sekar K, Lee Chong S, Seshachalam VP, Ling WH, Jin Phua CZ, Lai H, Yang H, Lu B, Lim JQ, Ma S, Chew SC, Chua KP, Santiago Alvarez JJ, Wu L, Ooi L, Yaw-Fui Chung A, Cheow PC, Kam JH, Wei-Chieh Kow A, Ganpathi IS, Bunchaliew C, Thammasiri J, Koh PS, Bee-Lan Ong D, Lim J, de Villa VH, Dela Cruz RD, Loh TJ, Wan WK, Leow WQ, Yang Y, Liu J, Skanderup AJ, Pang YH, Ting Soon GS, Madhavan K, Kiat-Hon Lim T, Bonney G, Goh BKP, Chew V, Dan YY, Toh HC, Sik-Yin Foo R, Tam WL, Zhai W, Kah-Hoe Chow P. Chen J, et al. Among authors: loh tj. J Hepatol. 2024 Oct;81(4):667-678. doi: 10.1016/j.jhep.2024.05.017. Epub 2024 May 21. J Hepatol. 2024. PMID: 38782118 Free article.
A genomic enhancer signature associates with hepatocellular carcinoma prognosis.
Jeon AJ, Anene-Nzelu CG, Teo YY, Chong SL, Sekar K, Wu L, Chew SC, Chen J, Kendarsari RI, Lai H, Ling WH, Kaya NA, Lim JQ, Chung AYF, Cheow PC, Kam JH, Madhavan K, Kow A, Ganpathi IS, Lim TKH, Leow WQ, Loong S, Loh TJ, Wan WK, Soon GST, Pang YH, Yoong BK, Bee-Lan Ong D, Lim J, de Villa VH, Dela Cruz RD, Chanwat R, Thammasiri J, Bonney GK, Goh BKP, Foo RSY, Chow PK. Jeon AJ, et al. Among authors: loh tj. JHEP Rep. 2023 Feb 26;5(6):100715. doi: 10.1016/j.jhepr.2023.100715. eCollection 2023 Jun. JHEP Rep. 2023. PMID: 37168287 Free PMC article.
Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma.
Jeon AJ, Teo YY, Sekar K, Chong SL, Wu L, Chew SC, Chen J, Kendarsari RI, Lai H, Ling WH, Kaya NA, Lim JQ, Ramasamy A, Oguz G, Chung AY, Chan CY, Cheow PC, Kam JH, Madhavan K, Kow A, Ganpathi IS, Lim TKH, Leow WQ, Loong S, Loh TJ, Wan WK, Soon GST, Pang YH, Yoong BK, Ong DB, Lim J, de Villa VH, Cruz RDD, Chanwat R, Thammasiri J, Bonney GK, Goh BKP, Tucker-Kellogg G, Foo RSY, Chow PKH. Jeon AJ, et al. Among authors: loh tj. BMC Cancer. 2023 Feb 3;23(1):118. doi: 10.1186/s12885-022-10444-3. BMC Cancer. 2023. PMID: 36737737 Free PMC article.
41 results