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The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113.
Podlesainski D, Adeniyi ET, Gröner Y, Schulz F, Krisilia V, Rehberg N, Richter T, Sehr D, Xie H, Simons VE, Kiffe-Delf AL, Kaschani F, Ioerger TR, Kaiser M, Kalscheuer R. Podlesainski D, et al. Among authors: ioerger tr. Cell Chem Biol. 2024 Oct 17;31(10):1755-1771.e73. doi: 10.1016/j.chembiol.2024.06.002. Epub 2024 Jul 8. Cell Chem Biol. 2024. PMID: 38981479 Free article.
Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs.
Zhou Y, Sun H, Rapiejko AR, Vargas-Blanco DA, Martini MC, Chase MR, Joubran SR, Davis AB, Dainis JP, Kelly JM, Ioerger TR, Roberts LA, Fortune SM, Shell SS. Zhou Y, et al. Among authors: ioerger tr. J Biol Chem. 2023 Nov;299(11):105312. doi: 10.1016/j.jbc.2023.105312. Epub 2023 Oct 5. J Biol Chem. 2023. PMID: 37802316 Free PMC article.
A dose-response model for statistical analysis of chemical genetic interactions in CRISPRi screens.
Choudhery S, DeJesus MA, Srinivasan A, Rock J, Schnappinger D, Ioerger TR. Choudhery S, et al. Among authors: ioerger tr. bioRxiv [Preprint]. 2024 Feb 7:2023.08.03.551759. doi: 10.1101/2023.08.03.551759. bioRxiv. 2024. Update in: PLoS Comput Biol. 2024 May 20;20(5):e1011408. doi: 10.1371/journal.pcbi.1011408 PMID: 37577548 Free PMC article. Updated. Preprint.
Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex.
Vargas R Jr, Luna MJ, Freschi L, Marin M, Froom R, Murphy KC, Campbell EA, Ioerger TR, Sassetti CM, Farhat MR. Vargas R Jr, et al. Among authors: ioerger tr. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2301394120. doi: 10.1073/pnas.2301394120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399390 Free PMC article.
147 results