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Targeting Smurf1 to block PDK1-Akt signaling in KRAS-mutated colorectal cancer.
Peng Z, Fang W, Wu B, He M, Li S, Wei J, Hao Y, Jin L, Liu M, Zhang X, Wei Y, Ge Y, Wei Y, Qian H, Zhang Y, Jiang J, Chang Z, Rao Y, Zhang X, Cui CP, Zhang L. Peng Z, et al. Among authors: he m. Nat Chem Biol. 2025 Jan;21(1):59-70. doi: 10.1038/s41589-024-01683-5. Epub 2024 Jul 22. Nat Chem Biol. 2025. PMID: 39039255
PROTACs: great opportunities for academia and industry.
Sun X, Gao H, Yang Y, He M, Wu Y, Song Y, Tong Y, Rao Y. Sun X, et al. Among authors: he m. Signal Transduct Target Ther. 2019 Dec 24;4:64. doi: 10.1038/s41392-019-0101-6. eCollection 2019. Signal Transduct Target Ther. 2019. PMID: 31885879 Free PMC article. Review.
Chemistries of bifunctional PROTAC degraders.
Cao C, He M, Wang L, He Y, Rao Y. Cao C, et al. Among authors: he y, he m. Chem Soc Rev. 2022 Aug 15;51(16):7066-7114. doi: 10.1039/d2cs00220e. Chem Soc Rev. 2022. PMID: 35916511 Review.
Centrosome anchoring regulates progenitor properties and cortical formation.
Shao W, Yang J, He M, Yu XY, Lee CH, Yang Z, Joyner AL, Anderson KV, Zhang J, Tsou MB, Shi H, Shi SH. Shao W, et al. Among authors: he m. Nature. 2020 Apr;580(7801):106-112. doi: 10.1038/s41586-020-2139-6. Epub 2020 Mar 25. Nature. 2020. PMID: 32238932 Free PMC article.
Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, Brophy ML, Liu X, Wylie-Sears J, Wu H, Wong S, Cui G, Kawashima Y, Matsumoto H, Kodera Y, Wojcikiewicz RJH, Srivastava S, Bischoff J, Wang DZ, Ley K, Chen H. Dong Y, et al. Among authors: he m. Nat Commun. 2020 Aug 7;11(1):3984. doi: 10.1038/s41467-020-17848-4. Nat Commun. 2020. PMID: 32770009 Free PMC article.
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