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621 results

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Page 1
Taming Lynch Syndrome: The Remarkable Power of Prevention for One Family.
Yurgelun MB, Rhees J, Papadopoulos N, Vogelstein B, Boland CR. Yurgelun MB, et al. Among authors: vogelstein b. Gastroenterology. 2024 Jul 20:S0016-5085(24)05224-7. doi: 10.1053/j.gastro.2024.06.037. Online ahead of print. Gastroenterology. 2024. PMID: 39038760 No abstract available.
ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1.
Rincon-Torroella J, Dal Molin M, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad NS, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, Gabrielson K, Sur S. Rincon-Torroella J, et al. Among authors: vogelstein b. bioRxiv [Preprint]. 2024 Jul 29:2023.07.23.550207. doi: 10.1101/2023.07.23.550207. bioRxiv. 2024. PMID: 37546808 Free PMC article. Preprint.
Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape.
Cook AL, Sur S, Dobbyn L, Watson E, Cohen JD, Ptak B, Lee BS, Paul S, Hsiue E, Popoli M, Vogelstein B, Papadopoulos N, Bettegowda C, Gabrielson K, Zhou S, Kinzler KW, Wyhs N. Cook AL, et al. Among authors: vogelstein b. bioRxiv [Preprint]. 2024 Jun 10:2023.12.28.573594. doi: 10.1101/2023.12.28.573594. bioRxiv. 2024. PMID: 38234817 Free PMC article. Preprint.
Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM.
Pearlman AH, Wang Y, Kalluri A, Parker M, Cohen JD, Dudley J, Rincon-Torroella J, Xia Y, Gensler R, Horwitz MA, Theodore J, Dobbyn L, Popoli M, Ptak J, Silliman N, Judge K, Groves M, Jackson CM, Jackson EM, Jallo GI, Lim M, Luciano M, Mukherjee D, Naidoo J, Rozati S, Sterling CH, Weingart J, Koschmann C, Mansoori A, Glantz M, Kamson D, Schreck KC, Pardo CA, Holdhoff M, Paul S, Kinzler KW, Papadopoulos N, Vogelstein B, Douville C, Bettegowda C. Pearlman AH, et al. Among authors: vogelstein b. medRxiv [Preprint]. 2024 Dec 4:2024.12.02.24318303. doi: 10.1101/2024.12.02.24318303. medRxiv. 2024. PMID: 39677487 Free PMC article. Preprint.
Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities.
Mog BJ, Marcou N, DiNapoli SR, Pearlman AH, Nichakawade TD, Hwang MS, Douglass J, Hsiue EH, Glavaris S, Wright KM, Konig MF, Paul S, Wyhs N, Ge J, Miller MS, Azurmendi P, Watson E, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Mog BJ, et al. Among authors: vogelstein b. Sci Transl Med. 2024 Jul 10;16(755):eadg7123. doi: 10.1126/scitranslmed.adg7123. Epub 2024 Jul 10. Sci Transl Med. 2024. PMID: 38985855
TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers.
Nichakawade TD, Ge J, Mog BJ, Lee BS, Pearlman AH, Hwang MS, DiNapoli SR, Wyhs N, Marcou N, Glavaris S, Konig MF, Gabelli SB, Watson E, Sterling C, Wagner-Johnston N, Rozati S, Swinnen L, Fuchs E, Pardoll DM, Gabrielson K, Papadopoulos N, Bettegowda C, Kinzler KW, Zhou S, Sur S, Vogelstein B, Paul S. Nichakawade TD, et al. Among authors: vogelstein b. Nature. 2024 Apr;628(8007):416-423. doi: 10.1038/s41586-024-07233-2. Epub 2024 Mar 27. Nature. 2024. PMID: 38538786
Machine learning to detect the SINEs of cancer.
Douville C, Lahouel K, Kuo A, Grant H, Avigdor BE, Curtis SD, Summers M, Cohen JD, Wang Y, Mattox A, Dudley J, Dobbyn L, Popoli M, Ptak J, Nehme N, Silliman N, Blair C, Romans K, Thoburn C, Gizzi J, Schoen RE, Tie J, Gibbs P, Ho-Pham LT, Tran BNH, Tran TS, Nguyen TV, Goggins M, Wolfgang CL, Wang TL, Shih IM, Lennon AM, Hruban RH, Bettegowda C, Kinzler KW, Papadopoulos N, Vogelstein B, Tomasetti C. Douville C, et al. Among authors: vogelstein b. Sci Transl Med. 2024 Jan 24;16(731):eadi3883. doi: 10.1126/scitranslmed.adi3883. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266106 Free PMC article.
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. Wright KM, et al. Among authors: vogelstein b. Nat Commun. 2023 Aug 21;14(1):5063. doi: 10.1038/s41467-023-40821-w. Nat Commun. 2023. PMID: 37604828 Free PMC article.
621 results