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Gut commensal metabolite rhamnose promotes macrophages phagocytosis by activating SLC12A4 and protects against sepsis in mice.
Li D, Wei R, Zhang X, Gong S, Wan M, Wang F, Li J, Chen M, Liu R, Wan Y, Hong Y, Zeng Z, Gu P, Wang Z, Selva Nandakumar K, Jiang Y, Zhou H, Chen P. Li D, et al. Among authors: wang f, wang z. Acta Pharm Sin B. 2024 Jul;14(7):3068-3085. doi: 10.1016/j.apsb.2024.03.025. Epub 2024 Mar 22. Acta Pharm Sin B. 2024. PMID: 39027244 Free PMC article.
Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsis.
Li J, Chen Y, Li R, Zhang X, Chen T, Mei F, Liu R, Chen M, Ge Y, Hu H, Wei R, Chen Z, Fan H, Zeng Z, Deng Y, Luo H, Hu S, Cai S, Wu F, Shi N, Wang Z, Zeng Y, Xie M, Jiang Y, Chen Z, Jia W, Chen P. Li J, et al. Among authors: wang z. Mol Ther. 2023 Apr 5;31(4):1017-1032. doi: 10.1016/j.ymthe.2023.01.018. Epub 2023 Jan 24. Mol Ther. 2023. PMID: 36698311 Free PMC article.
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Zeng Y, Wu R, Wang F, Li S, Li L, Li Y, Qin P, Wei M, Yang J, Wu J, Chen A, Ke G, Yan Z, Yang H, Chen Z, Wang Z, Xiao W, Jiang Y, Chen X, Zeng Z, Zhao X, Chen P, Gong S. Zeng Y, et al. Among authors: wang f, wang z. Cell Host Microbe. 2023 May 10;31(5):766-780.e7. doi: 10.1016/j.chom.2023.04.002. Epub 2023 Apr 25. Cell Host Microbe. 2023. PMID: 37100057 Free article.
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease.
Liang W, Yang Y, Gong S, Wei M, Ma Y, Feng R, Gao J, Liu X, Tu F, Ma W, Yi X, Liang Z, Wang F, Wang L, Chen D, Shu W, Miller BE, Tal-Singer R, Donaldson GC, Wedzicha JA, Singh D, Wilkinson TMA, Brightling CE, Chen R, Zhong N, Wang Z. Liang W, et al. Among authors: wang f, wang l, wang z. Cell Host Microbe. 2023 Jun 14;31(6):1054-1070.e9. doi: 10.1016/j.chom.2023.04.018. Epub 2023 May 18. Cell Host Microbe. 2023. PMID: 37207649 Free article.
β-resorcylic acid released by Limosilactobacillus reuteri protects against cisplatin-induced ovarian toxicity and infertility.
Feng Y, Zheng H, Yin C, Liang D, Zhang S, Chen J, Mai F, Lan Z, Zhu M, Mai Z, Shen S, Jayawardana T, Wu R, Tang W, Zhang R, He X, Zheng S, Hu Q, Han Y, Yang Y, Gong S, Wang Z, El-Omar EM, Luo W, Chen X, Chen G, Li P, Chen X. Feng Y, et al. Among authors: wang z. Cell Rep Med. 2024 Aug 20;5(8):101678. doi: 10.1016/j.xcrm.2024.101678. Epub 2024 Aug 2. Cell Rep Med. 2024. PMID: 39096912 Free PMC article.
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