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The fate of secretory cells during intestinal homeostasis, regeneration, and tumor formation is regulated by Tcf4.
Janeckova L, Stastna M, Hrckulak D, Berkova L, Kubovciak J, Onhajzer J, Kriz V, Dostalikova S, Mullerova T, Vecerkova K, Tenglerova M, Coufal S, Kostovcikova K, Blumberg RS, Filipp D, Basler K, Valenta T, Kolar M, Korinek V. Janeckova L, et al. Among authors: filipp d. bioRxiv [Preprint]. 2024 Jul 11:2024.07.11.603019. doi: 10.1101/2024.07.11.603019. bioRxiv. 2024. PMID: 39026783 Free PMC article. Preprint.
IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum.
Brabec T, Vobořil M, Schierová D, Valter E, Šplíchalová I, Dobeš J, Březina J, Dobešová M, Aidarova A, Jakubec M, Manning J, Blumberg R, Waisman A, Kolář M, Kubovčiak J, Šrůtková D, Hudcovic T, Schwarzer M, Froňková E, Pinkasová T, Jabandžiev P, Filipp D. Brabec T, et al. Among authors: filipp d. Mucosal Immunol. 2023 Aug;16(4):373-385. doi: 10.1016/j.mucimm.2023.01.005. Epub 2023 Feb 3. Mucosal Immunol. 2023. PMID: 36739089 Free article.
Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation.
Vobořil M, Brabec T, Dobeš J, Šplíchalová I, Březina J, Čepková A, Dobešová M, Aidarova A, Kubovčiak J, Tsyklauri O, Štěpánek O, Beneš V, Sedláček R, Klein L, Kolář M, Filipp D. Vobořil M, et al. Among authors: filipp d. Nat Commun. 2020 May 12;11(1):2361. doi: 10.1038/s41467-020-16081-3. Nat Commun. 2020. PMID: 32398640 Free PMC article.
FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation.
Dibus N, Zobalova E, Monleon MAM, Korinek V, Filipp D, Petrusova J, Sedlacek R, Kasparek P, Cermak L. Dibus N, et al. Among authors: filipp d. Front Cell Dev Biol. 2022 Jun 13;10:914053. doi: 10.3389/fcell.2022.914053. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35769260 Free PMC article.
Segmented filamentous bacteria-induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover.
Brabec T, Schwarzer M, Kováčová K, Dobešová M, Schierová D, Březina J, Pacáková I, Šrůtková D, Ben-Nun O, Goldfarb Y, Šplíchalová I, Kolář M, Abramson J, Filipp D, Dobeš J. Brabec T, et al. Among authors: filipp d. J Exp Med. 2024 Jan 1;221(1):e20230194. doi: 10.1084/jem.20230194. Epub 2023 Oct 30. J Exp Med. 2024. PMID: 37902602 Free PMC article.
51 results