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UBE2N: Hope on the Cancer Front, How to Inhibit This Promising Target Prospect?
Schwalen F, Ghadi C, Ibazizene L, Khan SU, Sopkova-de Oliveira Santos J, Weiswald LB, Voisin-Chiret AS, Meryet-Figuiere M, Kieffer C. Schwalen F, et al. Among authors: kieffer c. J Med Chem. 2025 Jan 13. doi: 10.1021/acs.jmedchem.4c01517. Online ahead of print. J Med Chem. 2025. PMID: 39806871 Review.
Towards New Anti-Inflammatory Agents: Design, Synthesis and Evaluation of Molecules Targeting XIAP-BIR2.
Farag M, Guedeney N, Schwalen F, Zadoroznyj A, Barczyk A, Giret M, Antraygues K, Wang A, Cornu M, Suzanne P, Since M, Sophie Voisin-Chiret A, Dubrez L, Leleu-Chavain N, Kieffer C, Sopkova-de Oliveira Santos J. Farag M, et al. Among authors: kieffer c. ChemMedChem. 2025 Jan 14;20(2):e202400567. doi: 10.1002/cmdc.202400567. Epub 2024 Nov 12. ChemMedChem. 2025. PMID: 39364702
Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling.
Rivera-Cardona J, Kakuturu N, Rowland EF, Teo QW, Thayer EA, Tan TJC, Sun J, Kieffer C, Wu NC, Brooke CB. Rivera-Cardona J, et al. Among authors: kieffer c. bioRxiv [Preprint]. 2024 Jul 12:2024.07.11.603146. doi: 10.1101/2024.07.11.603146. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Dec 12;20(12):e1012727. doi: 10.1371/journal.ppat.1012727 PMID: 39026731 Free PMC article. Updated. Preprint.
Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound.
Kieffer C, Primas N, Hutter S, Merckx A, Reininger L, Bach S, Ruchaud S, Gaillard F, Laget M, Amrane D, Hervé L, Castera-Ducros C, Renault J, Dumètre A, Rault S, Doerig C, Rathelot P, Vanelle P, Azas N, Verhaeghe P. Kieffer C, et al. Bioorg Med Chem. 2024 Mar 15;102:117654. doi: 10.1016/j.bmc.2024.117654. Epub 2024 Feb 28. Bioorg Med Chem. 2024. PMID: 38452406 Free article.
Molecular glue degraders: exciting opportunities for novel drug discovery.
Lemaitre T, Cornu M, Schwalen F, Since M, Kieffer C, Voisin-Chiret AS. Lemaitre T, et al. Among authors: kieffer c. Expert Opin Drug Discov. 2024 Apr;19(4):433-449. doi: 10.1080/17460441.2024.2306845. Epub 2024 Jan 24. Expert Opin Drug Discov. 2024. PMID: 38240114 Review.
Vulnerability of Older Adults to Government Impersonation Scams.
Yu L, Mottola G, Kieffer CN, Mascio R, Valdes O, Bennett DA, Boyle PA. Yu L, et al. Among authors: kieffer cn. JAMA Netw Open. 2023 Sep 5;6(9):e2335319. doi: 10.1001/jamanetworkopen.2023.35319. JAMA Netw Open. 2023. PMID: 37738048 Free PMC article.
63 results