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Page 1
Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis.
Jaquish A, Phung E, Gong X, Baldominos-Flores P, Galvan-Pena S, Bursulaya I, Magill I; ImmgenT consortium; Bertrand K, Chambers C, Agudo J, Mathis D, Benoist C, Ramanan D. Jaquish A, et al. Among authors: agudo j. bioRxiv [Preprint]. 2024 Jul 13:2024.07.09.602739. doi: 10.1101/2024.07.09.602739. bioRxiv. 2024. PMID: 39026711 Free PMC article. Preprint.
An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer.
Shimada K, Michaud DE, Cui YX, Zheng K, Goldberg J, Ju Z, Schnitt SJ, Pastorello R, Kania LD, Hoffer J, Muhlich JL, Hyun N, Krueger R, Gottlieb A, Nelson A, Wanderley CW, Antonellis G, McAllister SS, Tolaney SM, Waks AG, Jeselsohn R, Sorger PK, Agudo J, Mittendorf EA, Guerriero JL. Shimada K, et al. Among authors: agudo j. bioRxiv [Preprint]. 2024 Nov 25:2024.11.23.619172. doi: 10.1101/2024.11.23.619172. bioRxiv. 2024. PMID: 39651157 Free PMC article. Preprint.
Linking tumor immune infiltration to enhanced longevity in recurrence-free breast cancer.
Angelats L, Paré L, Rubio-Perez C, Sanfeliu E, González A, Seguí E, Villacampa G, Marín-Aguilera M, Pernas S, Conte B, Albarrán-Fernández V, Martínez-Sáez O, Aguirre Á, Galván P, Fernandez-Martinez A, Cobo S, Rey M, Martínez-Romero A, Walbaum B, Schettini F, Vidal M, Buckingham W, Muñoz M, Adamo B, Agrawal Y, Guedan S, Pascual T, Agudo J, Grzelak M, Borcherding N, Heyn H, Vivancos A, Parker JS, Villagrasa P, Perou CM, Prat A, Brasó-Maristany F. Angelats L, et al. Among authors: agudo j. ESMO Open. 2025 Jan 6;10(1):104109. doi: 10.1016/j.esmoop.2024.104109. Online ahead of print. ESMO Open. 2025. PMID: 39765189 Free article.
Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.
Kader T, Lin JR, Hug CB, Coy S, Chen YA, de Bruijn I, Shih N, Jung E, Pelletier RJ, Lopez Leon M, Mingo G, Omran DK, Lee JS, Yapp C, Satravada BA, Kundra R, Xu Y, Chan S, Tefft JB, Muhlich JL, Kim SH, Gysler SM, Agudo J, Heath JR, Schultz N, Drescher CW, Sorger PK, Drapkin R, Santagata S. Kader T, et al. Among authors: agudo j. Cancer Discov. 2024 Dec 20. doi: 10.1158/2159-8290.CD-24-1366. Online ahead of print. Cancer Discov. 2024. PMID: 39704522
Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.
Kader T, Lin JR, Hug C, Coy S, Chen YA, de Bruijn I, Shih N, Jung E, Pelletier RJ, Leon ML, Mingo G, Omran DK, Lee JS, Yapp C, Satravada BA, Kundra R, Xu Y, Chan S, Tefft JB, Muhlich J, Kim S, Gysler SM, Agudo J, Heath JR, Schultz N, Drescher C, Sorger PK, Drapkin R, Santagata S. Kader T, et al. Among authors: agudo j. bioRxiv [Preprint]. 2024 Sep 27:2024.09.25.615007. doi: 10.1101/2024.09.25.615007. bioRxiv. 2024. Update in: Cancer Discov. 2024 Dec 20. doi: 10.1158/2159-8290.CD-24-1366 PMID: 39386723 Free PMC article. Updated. Preprint.
Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity.
Fontana P, Du G, Zhang Y, Zhang H, Vora SM, Hu JJ, Shi M, Tufan AB, Healy LB, Xia S, Lee DJ, Li Z, Baldominos P, Ru H, Luo HR, Agudo J, Lieberman J, Wu H. Fontana P, et al. Among authors: agudo j. Cell. 2024 Oct 31;187(22):6165-6181.e22. doi: 10.1016/j.cell.2024.08.007. Epub 2024 Sep 6. Cell. 2024. PMID: 39243763
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes.
You Y, Dunst J, Ye K, Sandoz PA, Reinhardt A, Sandrock I, Comet NR, Sarkar RD, Yang E, Duprez E, Agudo J, Brown BD, Utz PJ, Kastenmüller W, Gerlach C, Prinz I, Önfelt B, Kreslavsky T. You Y, et al. Among authors: agudo j. Nat Immunol. 2024 Aug;25(8):1367-1382. doi: 10.1038/s41590-024-01899-6. Epub 2024 Jul 11. Nat Immunol. 2024. PMID: 38992254 Free PMC article.
SOX17 enables immune evasion of early colorectal adenomas and cancers.
Goto N, Westcott PMK, Goto S, Imada S, Taylor MS, Eng G, Braverman J, Deshpande V, Jacks T, Agudo J, Yilmaz ÖH. Goto N, et al. Among authors: agudo j. Nature. 2024 Mar;627(8004):636-645. doi: 10.1038/s41586-024-07135-3. Epub 2024 Feb 28. Nature. 2024. PMID: 38418875
74 results