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Page 1
Altered oxidative neurometabolic response to methylene blue in bipolar disorder revealed by quantitative neuroimaging.
Russo A, Örzsik B, Yalin N, Simpson I, Nwaubani P, Pinna A, De Marco R, Sharp H, Kartar A, Singh N, Blockley N, Stone AJL, Turkheimer FE, Young AH, Cercignani M, Zelaya F, Asllani I, Colasanti A. Russo A, et al. Among authors: simpson i. J Affect Disord. 2024 Oct 1;362:790-798. doi: 10.1016/j.jad.2024.07.029. Epub 2024 Jul 15. J Affect Disord. 2024. PMID: 39019231 Free article. Clinical Trial.
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
Mlynarski SN, Aquila BM, Cantin S, Cook S, Doshi A, Finlay MRV, Gangl ET, Grebe T, Gu C, Kawatkar SP, Petersen J, Pop-Damkov P, Schuller AG, Shao W, Shields JD, Simpson I, Tavakoli S, Tentarelli S, Throner S, Wang H, Wang J, Wu D, Ye Q. Mlynarski SN, et al. Among authors: simpson i. J Med Chem. 2024 Dec 12;67(23):20827-20841. doi: 10.1021/acs.jmedchem.4c02309. Epub 2024 Nov 21. J Med Chem. 2024. PMID: 39572889
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Shields JD, Aquila BM, Emmons D, Finlay MRV, Gangl ET, Gu C, Mlynarski SN, Petersen J, Pop-Damkov P, Sha L, Simpson I, Tavakoli S, Tentarelli S, Wang H, Ye Q, Zheng X. Shields JD, et al. Among authors: simpson i. J Med Chem. 2024 Dec 12;67(23):20799-20826. doi: 10.1021/acs.jmedchem.4c02295. Epub 2024 Nov 14. J Med Chem. 2024. PMID: 39540340
The pace of change of summertime temperature extremes.
McKinnon KA, Simpson IR, Williams AP. McKinnon KA, et al. Among authors: simpson ir. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2406143121. doi: 10.1073/pnas.2406143121. Epub 2024 Oct 7. Proc Natl Acad Sci U S A. 2024. PMID: 39374381 Free PMC article.
BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.
Nesic K, Krais JJ, Wang Y, Vandenberg CJ, Patel P, Cai KQ, Kwan T, Lieschke E, Ho GY, Barker HE, Bedo J, Casadei S, Farrell A, Radke M, Shield-Artin K, Penington JS, Geissler F, Kyran E, Betsch R, Xu L, Zhang F, Dobrovic A, Olesen I, Kristeleit R, Oza A, McNeish I, Ratnayake G, Traficante N; Australian Ovarian Cancer Study; DeFazio A, Bowtell DDL, Harding TC, Lin K, Swisher EM, Kondrashova O, Scott CL, Johnson N, Wakefield MJ. Nesic K, et al. Mol Cancer. 2024 Aug 5;23(1):158. doi: 10.1186/s12943-024-02048-1. Mol Cancer. 2024. PMID: 39103848 Free PMC article.
639 results