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Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.
Johnson-Martínez JP, Diener C, Levine AE, Wilmanski T, Suskind DL, Ralevski A, Hadlock J, Magis AT, Hood L, Rappaport N, Gibbons SM. Johnson-Martínez JP, et al. bioRxiv [Preprint]. 2024 Mar 9:2023.03.04.531100. doi: 10.1101/2023.03.04.531100. bioRxiv. 2024. Update in: Cell Rep Med. 2024 Jul 16;5(7):101646. doi: 10.1016/j.xcrm.2024.101646 PMID: 36945445 Free PMC article. Updated. Preprint.