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PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies.
Basavaraja R, Zhang H, Holczbauer Á, Lu Z, Radaelli E, Assenmacher CA, George SS, Nallamala VC, Beiting DP, Meyer-Ficca ML, Meyer RG, Guo W, Fan Y, Modzelewski AJ, Spiegelman VS, Cohen MS, Fuchs SY. Basavaraja R, et al. Among authors: assenmacher ca. Cell Rep Med. 2024 Jul 16;5(7):101649. doi: 10.1016/j.xcrm.2024.101649. Cell Rep Med. 2024. PMID: 39019005 Free PMC article.
Nuclear pleomorphism in canine cutaneous mast cell tumors: Comparison of reproducibility and prognostic relevance between estimates, manual morphometry, and algorithmic morphometry.
Haghofer A, Parlak E, Bartel A, Donovan TA, Assenmacher CA, Bolfa P, Dark MJ, Fuchs-Baumgartinger A, Klang A, Jäger K, Klopfleisch R, Merz S, Richter B, Schulman FY, Janout H, Ganz J, Scharinger J, Aubreville M, Winkler SM, Kiupel M, Bertram CA. Haghofer A, et al. Among authors: assenmacher ca. Vet Pathol. 2024 Nov 19:3009858241295399. doi: 10.1177/03009858241295399. Online ahead of print. Vet Pathol. 2024. PMID: 39560067 Free article.
Automated Nuclear Morphometry: A Deep Learning Approach for Prognostication in Canine Pulmonary Carcinoma to Enhance Reproducibility.
Glahn I, Haghofer A, Donovan TA, Degasperi B, Bartel A, Kreilmeier-Berger T, Hyndman PS, Janout H, Assenmacher CA, Bartenschlager F, Bolfa P, Dark MJ, Klang A, Klopfleisch R, Merz S, Richter B, Schulman FY, Ganz J, Scharinger J, Aubreville M, Winkler SM, Bertram CA. Glahn I, et al. Among authors: assenmacher ca. Vet Sci. 2024 Jun 17;11(6):278. doi: 10.3390/vetsci11060278. Vet Sci. 2024. PMID: 38922025 Free PMC article.
Computer-assisted mitotic count using a deep learning-based algorithm improves interobserver reproducibility and accuracy.
Bertram CA, Aubreville M, Donovan TA, Bartel A, Wilm F, Marzahl C, Assenmacher CA, Becker K, Bennett M, Corner S, Cossic B, Denk D, Dettwiler M, Gonzalez BG, Gurtner C, Haverkamp AK, Heier A, Lehmbecker A, Merz S, Noland EL, Plog S, Schmidt A, Sebastian F, Sledge DG, Smedley RC, Tecilla M, Thaiwong T, Fuchs-Baumgartinger A, Meuten DJ, Breininger K, Kiupel M, Maier A, Klopfleisch R. Bertram CA, et al. Among authors: assenmacher ca. Vet Pathol. 2022 Mar;59(2):211-226. doi: 10.1177/03009858211067478. Epub 2021 Dec 30. Vet Pathol. 2022. PMID: 34965805 Free PMC article.
Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris.
Lee J, Lundgren DK, Mao X, Manfredo-Vieira S, Nunez-Cruz S, Williams EF, Assenmacher CA, Radaelli E, Oh S, Wang B, Ellebrecht CT, Fraietta JA, Milone MC, Payne AS. Lee J, et al. Among authors: assenmacher ca. J Clin Invest. 2020 Dec 1;130(12):6317-6324. doi: 10.1172/JCI138416. J Clin Invest. 2020. PMID: 32817591 Free PMC article.
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality.
Demarco B, Grayczyk JP, Bjanes E, Le Roy D, Tonnus W, Assenmacher CA, Radaelli E, Fettrelet T, Mack V, Linkermann A, Roger T, Brodsky IE, Chen KW, Broz P. Demarco B, et al. Among authors: assenmacher ca. Sci Adv. 2020 Nov 18;6(47):eabc3465. doi: 10.1126/sciadv.abc3465. Print 2020 Nov. Sci Adv. 2020. PMID: 33208362 Free PMC article.
Pathology of macrophage activation syndrome in humanized NSGS mice.
Tarrant JC, Binder ZA, Bugatti M, Vermi W, van den Oord J, Ranieri B, Assenmacher CA, Hoepp N, O'Rourke DM, Shan X, Danet-Desnoyers G, Radaelli E. Tarrant JC, et al. Among authors: assenmacher ca. Res Vet Sci. 2021 Jan;134:137-146. doi: 10.1016/j.rvsc.2020.12.003. Epub 2020 Dec 16. Res Vet Sci. 2021. PMID: 33383491
54 results