Nissen P - Search Results

1

Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site.

Pedersen CN, Yang F, Ita S, Xu Y, Akunuri R, Trampari S, Neumann CMT, Desdorf LM, Schiøtt B, Salvino JM, Mortensen OV, Nissen P, Shahsavar A. Pedersen CN, et al. Among authors: nissen p. J Neurochem. 2024 Sep;168(9):2043-2055. doi: 10.1111/jnc.16179. Epub 2024 Jul 15. J Neurochem. 2024. PMID: 39010681

2

Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.

Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P. Bublitz M, et al. Among authors: nissen p. J Biol Chem. 2013 Apr 12;288(15):10759-65. doi: 10.1074/jbc.R112.436550. Epub 2013 Feb 11. J Biol Chem. 2013. PMID: 23400778 Free PMC article. Review.

3

Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase.

Paulsen ES, Villadsen J, Tenori E, Liu H, Bonde DF, Lie MA, Bublitz M, Olesen C, Autzen HE, Dach I, Sehgal P, Nissen P, Møller JV, Schiøtt B, Christensen SB. Paulsen ES, et al. Among authors: nissen p. J Med Chem. 2013 May 9;56(9):3609-19. doi: 10.1021/jm4001083. Epub 2013 Apr 30. J Med Chem. 2013. PMID: 23574308

4

A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.

Malinauskaite L, Said S, Sahin C, Grouleff J, Shahsavar A, Bjerregaard H, Noer P, Severinsen K, Boesen T, Schiøtt B, Sinning S, Nissen P. Malinauskaite L, et al. Among authors: nissen p. Nat Commun. 2016 May 25;7:11673. doi: 10.1038/ncomms11673. Nat Commun. 2016. PMID: 27221344 Free PMC article.

5

Expression strategies for structural studies of eukaryotic membrane proteins.

Lyons JA, Shahsavar A, Paulsen PA, Pedersen BP, Nissen P. Lyons JA, et al. Among authors: nissen p. Curr Opin Struct Biol. 2016 Jun;38:137-44. doi: 10.1016/j.sbi.2016.06.011. Epub 2016 Jun 27. Curr Opin Struct Biol. 2016. PMID: 27362979 Review.

6

A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.

Focht D, Neumann C, Lyons J, Eguskiza Bilbao A, Blunck R, Malinauskaite L, Schwarz IO, Javitch JA, Quick M, Nissen P. Focht D, et al. Among authors: nissen p. EMBO J. 2021 Jan 4;40(1):e105164. doi: 10.15252/embj.2020105164. Epub 2020 Nov 6. EMBO J. 2021. PMID: 33155685 Free PMC article.

7

Structural insights into the inhibition of glycine reuptake.

Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P. Shahsavar A, et al. Among authors: nissen p. Nature. 2021 Mar;591(7851):677-681. doi: 10.1038/s41586-021-03274-z. Epub 2021 Mar 3. Nature. 2021. PMID: 33658720

8

The Crystal Structure of the Ca²⁺-ATPase 1 from Listeria monocytogenes reveals a Pump Primed for Dephosphorylation.

Hansen SB, Dyla M, Neumann C, Quistgaard EMH, Andersen JL, Kjaergaard M, Nissen P. Hansen SB, et al. Among authors: nissen p. J Mol Biol. 2021 Aug 6;433(16):167015. doi: 10.1016/j.jmb.2021.167015. Epub 2021 Apr 30. J Mol Biol. 2021. PMID: 33933469 Free article.

9

Transport unplugged: KCCs are regulated through an N-terminal plug of the ion pathway.

Kock Flygaard R, Neumann C, Anthony Lyons J, Nissen P. Kock Flygaard R, et al. Among authors: nissen p. EMBO J. 2021 Jul 15;40(14):e108371. doi: 10.15252/embj.2021108371. Epub 2021 May 25. EMBO J. 2021. PMID: 34031898 Free PMC article.

10

Variations on a theme: crystal forms of the amino-acid transporter MhsT.

Neumann C, Focht D, Trampari S, Lyons JA, Nissen P. Neumann C, et al. Among authors: nissen p. Acta Crystallogr F Struct Biol Commun. 2022 Aug 1;78(Pt 8):297-305. doi: 10.1107/S2053230X22007154. Epub 2022 Jul 26. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 35924597 Free PMC article.

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