Abdel-Aziz AA - Search Results

1

Synthesis, enzyme inhibition assay, and molecular modeling study of novel pyrazolines linked to 4-methylsulfonylphenyl scaffold: antitumor activity and cell cycle analysis.

Abdel-Aziz AA, El-Azab AS, Brogi S, Ayyad RR, Alkahtani HM, Abuelizz HA, Al-Suwaidan IA, Al-Obaid AM. Abdel-Aziz AA, et al. RSC Adv. 2024 Jul 12;14(31):22132-22146. doi: 10.1039/d4ra03902e. eCollection 2024 Jul 12. RSC Adv. 2024. PMID: 39005246 Free PMC article.

2

Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs.

Al-Rashood ST, Aboldahab IA, Nagi MN, Abouzeid LA, Abdel-Aziz AA, Abdel-Hamide SG, Youssef KM, Al-Obaid AM, El-Subbagh HI. Al-Rashood ST, et al. Bioorg Med Chem. 2006 Dec 15;14(24):8608-21. doi: 10.1016/j.bmc.2006.08.030. Epub 2006 Sep 12. Bioorg Med Chem. 2006. PMID: 16971132

3

Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs.

Al-Obaid AM, Abdel-Hamide SG, El-Kashef HA, Abdel-Aziz AA, El-Azab AS, Al-Khamees HA, El-Subbagh HI. Al-Obaid AM, et al. Eur J Med Chem. 2009 Jun;44(6):2379-91. doi: 10.1016/j.ejmech.2008.09.015. Epub 2008 Sep 23. Eur J Med Chem. 2009. PMID: 18950904

4

Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones.

Al-Omary FA, Abou-Zeid LA, Nagi MN, Habib el-SE, Abdel-Aziz AA, El-Azab AS, Abdel-Hamide SG, Al-Omar MA, Al-Obaid AM, El-Subbagh HI. Al-Omary FA, et al. Bioorg Med Chem. 2010 Apr 15;18(8):2849-63. doi: 10.1016/j.bmc.2010.03.019. Epub 2010 Mar 12. Bioorg Med Chem. 2010. PMID: 20350811

5

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study.

El-Azab AS, Al-Omar MA, Abdel-Aziz AA, Abdel-Aziz NI, el-Sayed MA, Aleisa AM, Sayed-Ahmed MM, Abdel-Hamide SG. El-Azab AS, et al. Eur J Med Chem. 2010 Sep;45(9):4188-98. doi: 10.1016/j.ejmech.2010.06.013. Epub 2010 Jun 16. Eur J Med Chem. 2010. PMID: 20599299

6

Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.

El-Sayed MA, Abdel-Aziz NI, Abdel-Aziz AA, El-Azab AS, Asiri YA, Eltahir KE. El-Sayed MA, et al. Bioorg Med Chem. 2011 Jun 1;19(11):3416-24. doi: 10.1016/j.bmc.2011.04.027. Epub 2011 Apr 22. Bioorg Med Chem. 2011. PMID: 21570309

7

Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents.

Abdel-Aziz AA, El-Azab AS, Attia SM, Al-Obaid AM, Al-Omar MA, El-Subbagh HI. Abdel-Aziz AA, et al. Eur J Med Chem. 2011 Sep;46(9):4324-9. doi: 10.1016/j.ejmech.2011.07.002. Epub 2011 Jul 8. Eur J Med Chem. 2011. PMID: 21783284

8

Synthesis and anticonvulsant activity of some new thiazolo[3,2-a][1,3]diazepine, benzo[d]thiazolo[5,2-a][12,6]diazepine and benzo[d]oxazolo[5,2-a][12,6]diazepine analogues.

El-Subbagh HI, Hassan GS, El-Azab AS, Abdel-Aziz AA, Kadi AA, Al-Obaid AM, Al-Shabanah OA, Sayed-Ahmed MM. El-Subbagh HI, et al. Eur J Med Chem. 2011 Nov;46(11):5567-72. doi: 10.1016/j.ejmech.2011.09.021. Epub 2011 Sep 22. Eur J Med Chem. 2011. PMID: 21963116

9

Design, synthesis, single-crystal and preliminary antitumor activity of novel arenesulfonylimidazolidin-2-ones.

Abdel-Aziz AA, El-Azab AS, El-Subbagh HI, Al-Obaid AM, Alanazi AM, Al-Omar MA. Abdel-Aziz AA, et al. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2008-14. doi: 10.1016/j.bmcl.2012.01.036. Epub 2012 Jan 21. Bioorg Med Chem Lett. 2012. PMID: 22318157

10

5-Isopropyl-imidazolidine-2,4-dione monohydrate.

Abdel-Aziz AA, El-Azab AS, Al-Obaid AM, Hemamalini M, Fun HK. Abdel-Aziz AA, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o533. doi: 10.1107/S1600536812002838. Epub 2012 Jan 31. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22347129 Free PMC article.

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