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A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications.
Schön J, Barut GT, Trüeb BS, Halwe NJ, Berenguer Veiga I, Kratzel A, Ulrich L, Kelly JN, Brügger M, Wylezich C, Taddeo A, Aguiar Moreira E, Túrós D, Grau-Roma L, Ahrens AK, Schlottau K, Britzke T, Breithaupt A, Corleis B, Kochmann J, Oliveira Esteves BI, Almeida L, Thomann L, Devisme C, Stalder H, Steiner S, Ochsenbein S, Schmied K, Labroussaa F, Jores J, V'kovski P, Cmiljanovic V, Alves MP, Benarafa C, Ebert N, Hoffmann D, Beer M, Thiel V. Schön J, et al. Among authors: britzke t. Nat Microbiol. 2024 Aug;9(8):2099-2112. doi: 10.1038/s41564-024-01755-1. Epub 2024 Jul 12. Nat Microbiol. 2024. PMID: 38997518 Free PMC article.
Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Dos Reis VP, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel D, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. Among authors: britzke t. bioRxiv [Preprint]. 2024 Aug 9:2024.08.09.607272. doi: 10.1101/2024.08.09.607272. bioRxiv. 2024. PMID: 39149352 Free PMC article. Preprint.
High protection and transmission-blocking immunity elicited by single-cycle SARS-CoV-2 vaccine in hamsters.
Lett MJ, Otte F, Hauser D, Schön J, Kipfer ET, Hoffmann D, Halwe NJ, Breithaupt A, Ulrich L, Britzke T, Kochmann J, Corleis B, Zhang Y, Urda L, Cmiljanovic V, Lang C, Beer M, Mittelholzer C, Klimkait T. Lett MJ, et al. Among authors: britzke t. NPJ Vaccines. 2024 Oct 30;9(1):206. doi: 10.1038/s41541-024-00992-z. NPJ Vaccines. 2024. PMID: 39472701 Free PMC article.
H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Pinho Dos Reis V, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel DG, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. Among authors: britzke t. Nature. 2024 Sep 25. doi: 10.1038/s41586-024-08063-y. Online ahead of print. Nature. 2024. PMID: 39321846