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Page 1
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research.
Ibanez L, Liu M, Beric A, Timsina J, Kohlfeld P, Bergmann K, Lowery J, Sykora N, Sanchez-Montejo B, Brock W, Budde JP, Bateman RJ, Barthelemy N, Schindler SE, Holtzman DM, Benzinger TLS, Xiong C, Tarawneh R, Moulder K, Morris JC, Sung YJ, Cruchaga C. Ibanez L, et al. Among authors: timsina j. Alzheimers Dement. 2024 Nov 22. doi: 10.1002/alz.14413. Online ahead of print. Alzheimers Dement. 2024. PMID: 39575871
Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.
Wang C, Yang C, Western D, Ali M, Wang Y, Phuah CL, Budde J, Wang L, Gorijala P, Timsina J, Ruiz A, Pastor P, Fernandez MV; Dominantly Inherited Alzheimer Network (DIAN); Alzheimer’s Disease Neuroimaging Initiative (ADNI); Panyard DJ, Engelman CD, Deming Y, Boada M, Cano A, Garcia-Gonzalez P, Graff-Radford NR, Mori H, Lee JH, Perrin RJ, Ibanez L, Sung YJ, Cruchaga C. Wang C, et al. Among authors: timsina j. Nat Genet. 2024 Dec;56(12):2685-2695. doi: 10.1038/s41588-024-01973-7. Epub 2024 Nov 11. Nat Genet. 2024. PMID: 39528826
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.
Western D, Timsina J, Wang L, Wang C, Yang C, Phillips B, Wang Y, Liu M, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey AI, Morris JC, Perrin RJ, Ruiz A, Marquié M, Boada M, de Rojas I, Rutledge J, Oh H, Wilson EN, Le Guen Y, Reus LM, Tijms B, Visser PJ, van der Lee SJ, Pijnenburg YAL, Teunissen CE, Del Campo Milan M, Alvarez I, Aguilar M; Dominantly Inherited Alzheimer Network (DIAN); Alzheimer’s Disease Neuroimaging Initiative (ADNI); Greicius MD, Pastor P, Pulford DJ, Ibanez L, Wyss-Coray T, Sung YJ, Cruchaga C. Western D, et al. Among authors: timsina j. Nat Genet. 2024 Dec;56(12):2672-2684. doi: 10.1038/s41588-024-01972-8. Epub 2024 Nov 11. Nat Genet. 2024. PMID: 39528825
Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance.
Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, Hernández-Villamizar F, Lorenzini L, Del Campo M, Sanchez-Benavides G, Minguillon C, Navarro A, Cruchaga C, Suárez-Calvet M, Vilor-Tejedor N. Anastasi F, et al. Among authors: timsina j. Res Sq [Preprint]. 2024 Oct 18:rs.3.rs-5267673. doi: 10.21203/rs.3.rs-5267673/v1. Res Sq. 2024. PMID: 39483923 Free PMC article. Preprint.
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests.
Warmenhoven N, Salvadó G, Janelidze S, Mattsson-Carlgren N, Bali D, Orduña Dolado A, Kolb H, Triana-Baltzer G, Barthélemy NR, Schindler SE, Aschenbrenner AJ, Raji CA, Benzinger TLS, Morris JC, Ibanez L, Timsina J, Cruchaga C, Bateman RJ, Ashton N, Arslan B, Zetterberg H, Blennow K, Pichet Binette A, Hansson O. Warmenhoven N, et al. Among authors: timsina j. Brain. 2024 Oct 28:awae346. doi: 10.1093/brain/awae346. Online ahead of print. Brain. 2024. PMID: 39468767
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, Llibre-Guerra JJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV, Tarawneh R, McDade E, Morris JC, Bateman RJ, Goate A; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Among authors: timsina j. Cell. 2024 Oct 31;187(22):6309-6326.e15. doi: 10.1016/j.cell.2024.08.049. Epub 2024 Sep 26. Cell. 2024. PMID: 39332414 Free PMC article.
Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance.
Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, Hernández-Villamizar F, Lorenzini L, Del Campo M, Sánchez-Benavides G, Minguillon C, Navarro A, Cruchaga C, Suárez-Calvet M, Vilor-Tejedor N. Anastasi F, et al. Among authors: timsina j. medRxiv [Preprint]. 2024 Jul 24:2024.07.23.24310854. doi: 10.1101/2024.07.23.24310854. medRxiv. 2024. PMID: 39211866 Free PMC article. Preprint.
The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic Interpretation.
Wang G, Li Y, Xiong C, Cao Y, Schindler SE, McDade E, Blennow K, Hansson O, Dage JL, Jack CR Jr, Teunissen CE, Shaw LM, Zetterberg H, Laura I, Timsina J, Carlos C; DIAN-TU Study Team; Bateman RJ. Wang G, et al. Among authors: timsina j. medRxiv [Preprint]. 2024 Jul 27:2024.07.25.24311002. doi: 10.1101/2024.07.25.24311002. medRxiv. 2024. PMID: 39108526 Free PMC article. Preprint.
Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease.
McDade E, Liu H, Bui Q, Hassenstab J, Gordon B, Benzinger T, Shen Y, Timsina J, Wang L, Sung YJ, Karch C, Renton A, Daniels A, Morris J, Xiong C, Ibanez L, Perrin R, Llibre-Guerra JJ, Day G, Supnet-Bell C, Xu X, Berman S, Chhatwal J, Ikeuchi T, Kasuga K, Niimi Y, Huey E, Schofield P, Brooks W, Ryan N, Jucker M, Laske C, Levin J, Vöglein J, Roh JH, Lopera F, Bateman R, Cruchaga C. McDade E, et al. Among authors: timsina j. Res Sq [Preprint]. 2024 Jul 23:rs.3.rs-4202125. doi: 10.21203/rs.3.rs-4202125/v1. Res Sq. 2024. PMID: 39108475 Free PMC article. Preprint.
47 results