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Unique and redundant roles of mouse BCMA, TACI, BAFF, APRIL, and IL-6 in supporting antibody-producing cells in different tissues.
Eslami M, Schuepbach-Mallepell S, Diana D, Willen L, Kowalczyk-Quintas C, Desponds C, Peter B, Vigolo M, Renevey F, Donzé O, Luther SA, Yalkinoglu Ö, Alouche N, Schneider P. Eslami M, et al. Among authors: vigolo m. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2404309121. doi: 10.1073/pnas.2404309121. Epub 2024 Jul 11. Proc Natl Acad Sci U S A. 2024. PMID: 38990948 Free PMC article.
A Phase I Study of the Pan-Notch Inhibitor CB-103 for Patients with Advanced Adenoid Cystic Carcinoma and Other Tumors.
Hanna GJ, Stathis A, Lopez-Miranda E, Racca F, Quon D, Leyvraz S, Hess D, Keam B, Rodon J, Ahn MJ, Kim HR, Schneeweiss A, Ribera JM, DeAngelo D, Perez Garcia JM, Cortes J, Schönborn-Kellenberger O, Weber D, Pisa P, Bauer M, Beni L, Bobadilla M, Lehal R, Vigolo M, Vogl FD, Garralda E. Hanna GJ, et al. Among authors: vigolo m. Cancer Res Commun. 2023 Sep 14;3(9):1853-1861. doi: 10.1158/2767-9764.CRC-23-0333. Cancer Res Commun. 2023. PMID: 37712875 Free PMC article. Clinical Trial.
CB-103: A novel CSL-NICD inhibitor for the treatment of NOTCH-driven T-cell acute lymphoblastic leukemia: A case report of complete clinical response in a patient with relapsed and refractory T-ALL.
Medinger M, Junker T, Heim D, Tzankov A, Jermann PM, Bobadilla M, Vigolo M, Lehal R, Vogl FD, Bauer M, Passweg J. Medinger M, et al. Among authors: vigolo m. EJHaem. 2022 Jun 16;3(3):1009-1012. doi: 10.1002/jha2.510. eCollection 2022 Aug. EJHaem. 2022. PMID: 36051082 Free PMC article.
Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells.
Smulski CR, Zhang L, Burek M, Teixidó Rubio A, Briem JS, Sica MP, Sevdali E, Vigolo M, Willen L, Odermatt P, Istanbullu D, Herr S, Cavallari M, Hess H, Rizzi M, Eibel H, Schneider P. Smulski CR, et al. Among authors: vigolo m. Cell Rep. 2022 Mar 29;38(13):110583. doi: 10.1016/j.celrep.2022.110583. Cell Rep. 2022. PMID: 35354034 Free article.
Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.
Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK Jr, Roodman GD, Bellido T, Delgado-Calle J. Sabol HM, et al. Among authors: vigolo m. Cancer Res. 2021 Oct 1;81(19):5102-5114. doi: 10.1158/0008-5472.CAN-21-0524. Epub 2021 Aug 4. Cancer Res. 2021. PMID: 34348968 Free PMC article.
Methods for the Administration of EDAR Pathway Modulators in Mice.
Schuepbach-Mallepell S, Kowalczyk-Quintas C, Dick A, Eslami M, Vigolo M, Headon DJ, Cheeseman M, Schneider H, Schneider P. Schuepbach-Mallepell S, et al. Among authors: vigolo m. Methods Mol Biol. 2021;2248:167-183. doi: 10.1007/978-1-0716-1130-2_12. Methods Mol Biol. 2021. PMID: 33185875
Pharmacological disruption of the Notch transcription factor complex.
Lehal R, Zaric J, Vigolo M, Urech C, Frismantas V, Zangger N, Cao L, Berger A, Chicote I, Loubéry S, Choi SH, Koch U, Blacklow SC, Palmer HG, Bornhauser B, González-Gaitán M, Arsenijevic Y, Zoete V, Aster JC, Bourquin JP, Radtke F. Lehal R, et al. Among authors: vigolo m. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16292-16301. doi: 10.1073/pnas.1922606117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601208 Free PMC article.
No interactions between heparin and atacicept, an antagonist of B cell survival cytokines.
Kowalczyk-Quintas C, Willen D, Willen L, Golob M, Schuepbach-Mallepell S, Peter B, Eslami M, Vigolo M, Broly H, Samy E, Yalkinoglu Ö, Schneider P. Kowalczyk-Quintas C, et al. Among authors: vigolo m. Br J Pharmacol. 2019 Oct;176(20):4019-4033. doi: 10.1111/bph.14811. Epub 2019 Oct 15. Br J Pharmacol. 2019. PMID: 31355456 Free PMC article.
Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab.
Kowalczyk-Quintas C, Chevalley D, Willen L, Jandus C, Vigolo M, Schneider P. Kowalczyk-Quintas C, et al. Among authors: vigolo m. Front Immunol. 2018 Nov 20;9:2698. doi: 10.3389/fimmu.2018.02698. eCollection 2018. Front Immunol. 2018. PMID: 30524439 Free PMC article.
16 results