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The pros and confs of IL-18 activation.
Clancy DM, Andries J, Savvides SN. Clancy DM, et al. Among authors: savvides sn. Immunity. 2024 Jul 9;57(7):1445-1448. doi: 10.1016/j.immuni.2024.06.006. Immunity. 2024. PMID: 38986437
Catalytic cycle of human glutathione reductase near 1 A resolution.
Berkholz DS, Faber HR, Savvides SN, Karplus PA. Berkholz DS, et al. Among authors: savvides sn. J Mol Biol. 2008 Oct 3;382(2):371-84. doi: 10.1016/j.jmb.2008.06.083. Epub 2008 Jul 7. J Mol Biol. 2008. PMID: 18638483 Free PMC article.
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.
Bloch Y, Bouchareychas L, Merceron R, Składanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN. Bloch Y, et al. Among authors: savvides sn. Immunity. 2018 Jan 16;48(1):45-58.e6. doi: 10.1016/j.immuni.2017.12.008. Epub 2017 Dec 26. Immunity. 2018. PMID: 29287995 Free PMC article.
The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Brinkhaus M, Pannecoucke E, van der Kooi EJ, Bentlage AEH, Derksen NIL, Andries J, Balbino B, Sips M, Ulrichts P, Verheesen P, de Haard H, Rispens T, Savvides SN, Vidarsson G. Brinkhaus M, et al. Among authors: savvides sn. Nat Commun. 2022 Oct 14;13(1):6073. doi: 10.1038/s41467-022-33764-1. Nat Commun. 2022. PMID: 36241613 Free PMC article.
137 results