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Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE 3rd, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E, Shah SJ, Li Z, Lefer DJ. Doiron JE, et al. Among authors: yu x. Br J Pharmacol. 2024 Nov;181(21):4294-4310. doi: 10.1111/bph.16493. Epub 2024 Jul 9. Br J Pharmacol. 2024. PMID: 38982742
Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
Doiron JE, Elbatreek MH, Xia H, Yu X, Wilson Tang WH, LaPenna KB, Sharp TE, Goodchild TT, Xian M, Xu S, Quiriarte H, Allerton TD, Zagouras A, Wilcox J, Shah SJ, Pfeilschifter J, Beck KF, Li Z, Lefer DJ. Doiron JE, et al. Among authors: yu x. bioRxiv [Preprint]. 2024 Sep 19:2024.09.16.613349. doi: 10.1101/2024.09.16.613349. bioRxiv. 2024. PMID: 39345440 Free PMC article. Preprint.
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