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Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency.
Zakas PM, Cunningham SC, Doherty A, van Dijk EB, Ibraheim R, Yu S, Mekonnen BD, Lang B, English EJ, Sun G, Duncan MC, Benczkowski MS, Altshuler RC, Singh MJ, Kibbler ES, Tonga GY, Wang ZJ, Wang ZJ, Li G, An D, Rottman JB, Bhavsar Y, Purcell C, Jain R, Alberry R, Roquet N, Fu Y, Citorik RJ, Rubens JR, Holmes MC, Cotta-Ramusino C, Querbes W, Alexander IE, Salomon WE. Zakas PM, et al. Among authors: rubens jr. Mol Ther. 2024 Oct 2;32(10):3356-3371. doi: 10.1016/j.ymthe.2024.06.021. Epub 2024 Jul 8. Mol Ther. 2024. PMID: 38981468
Gene networks that compensate for crosstalk with crosstalk.
Müller IE, Rubens JR, Jun T, Graham D, Xavier R, Lu TK. Müller IE, et al. Among authors: rubens jr. Nat Commun. 2019 Sep 6;10(1):4028. doi: 10.1038/s41467-019-12021-y. Nat Commun. 2019. PMID: 31492904 Free PMC article.
Synthetic analog computation in living cells.
Daniel R, Rubens JR, Sarpeshkar R, Lu TK. Daniel R, et al. Among authors: rubens jr. Nature. 2013 May 30;497(7451):619-23. doi: 10.1038/nature12148. Epub 2013 May 15. Nature. 2013. PMID: 23676681
Alternative isoleucine synthesis pathway in cyanobacterial species.
Wu B, Zhang B, Feng X, Rubens JR, Huang R, Hicks LM, Pakrasi HB, Tang YJ. Wu B, et al. Among authors: rubens jr. Microbiology (Reading). 2010 Feb;156(Pt 2):596-602. doi: 10.1099/mic.0.031799-0. Epub 2009 Oct 29. Microbiology (Reading). 2010. PMID: 19875435 Free article.
18 results