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Computer-aided design and implementation of efficient biosynthetic pathways to produce high added-value products derived from tyrosine in Escherichia coli.
Ferreira S, Balola A, Sveshnikova A, Hatzimanikatis V, Vilaça P, Maia P, Carreira R, Stoney R, Carbonell P, Souza CS, Correia J, Lousa D, Soares CM, Rocha I. Ferreira S, et al. Among authors: hatzimanikatis v. Front Bioeng Biotechnol. 2024 Jun 24;12:1360740. doi: 10.3389/fbioe.2024.1360740. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 38978715 Free PMC article.
From microbiome composition to functional engineering, one step at a time.
Burz SD, Causevic S, Dal Co A, Dmitrijeva M, Engel P, Garrido-Sanz D, Greub G, Hapfelmeier S, Hardt W-D, Hatzimanikatis V, Heiman CM, Herzog MK-M, Hockenberry A, Keel C, Keppler A, Lee S-J, Luneau J, Malfertheiner L, Mitri S, Ngyuen B, Oftadeh O, Pacheco AR, Peaudecerf F, Resch G, Ruscheweyh H-J, Sahin A, Sanders IR, Slack E, Sunagawa S, Tackmann J, Tecon R, Ugolini GS, Vacheron J, van der Meer JR, Vayena E, Vonaesch P, Vorholt JA. Burz SD, et al. Among authors: hatzimanikatis v. Microbiol Mol Biol Rev. 2023 Dec 20;87(4):e0006323. doi: 10.1128/mmbr.00063-23. Epub 2023 Nov 10. Microbiol Mol Biol Rev. 2023. PMID: 37947420 Free PMC article. Review.
Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites.
Maurizio M, Masid M, Woods K, Caldelari R, Doench JG, Naguleswaran A, Joly D, González-Fernández M, Zemp J, Borteele M, Hatzimanikatis V, Heussler V, Rottenberg S, Olias P. Maurizio M, et al. Among authors: hatzimanikatis v. Nat Commun. 2024 Jul 21;15(1):6145. doi: 10.1038/s41467-024-50405-x. Nat Commun. 2024. PMID: 39034325 Free PMC article.
Rational strain design with minimal phenotype perturbation.
Narayanan B, Weilandt D, Masid M, Miskovic L, Hatzimanikatis V. Narayanan B, et al. Among authors: hatzimanikatis v. Nat Commun. 2024 Jan 24;15(1):723. doi: 10.1038/s41467-024-44831-0. Nat Commun. 2024. PMID: 38267425 Free PMC article.
Metabolic interaction models recapitulate leaf microbiota ecology.
Schäfer M, Pacheco AR, Künzler R, Bortfeld-Miller M, Field CM, Vayena E, Hatzimanikatis V, Vorholt JA. Schäfer M, et al. Among authors: hatzimanikatis v. Science. 2023 Jul 7;381(6653):eadf5121. doi: 10.1126/science.adf5121. Epub 2023 Jul 7. Science. 2023. PMID: 37410834
144 results