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CircHTT(2,3,4,5,6) - co-evolving with the HTT CAG-repeat tract - modulates Huntington's disease phenotypes.
Morandell J, Monziani A, Lazioli M, Donzel D, Döring J, Oss Pegorar C, D'Anzi A, Pellegrini M, Mattiello A, Bortolotti D, Bergonzoni G, Tripathi T, Mattis VB, Kovalenko M, Rosati J, Dieterich C, Dassi E, Wheeler VC, Ellederová Z, Wilusz JE, Viero G, Biagioli M. Morandell J, et al. Among authors: biagioli m. Mol Ther Nucleic Acids. 2024 Jun 3;35(3):102234. doi: 10.1016/j.omtn.2024.102234. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 38974999 Free PMC article.
Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4-/- Mice.
Di Giorgio C, Urbani G, Marchianò S, Biagioli M, Bordoni M, Bellini R, Massa C, Lachi G, Cari L, Morretta E, Spinelli L, Monti MC, Sepe V, Zampella A, Distrutti E, Banales JM, Lapitz A, Milkiewicz P, Milkiewicz M, Fiorucci S. Di Giorgio C, et al. Among authors: biagioli m. Liver Int. 2025 Feb;45(2):e16235. doi: 10.1111/liv.16235. Liver Int. 2025. PMID: 39804015 Free PMC article.
SINEUP RNA rescues molecular phenotypes associated with CHD8 suppression in autism spectrum disorder model systems.
Di Leva F, Arnoldi M, Santarelli S, Massonot M, Lemée MV, Bon C, Pellegrini M, Castellini ME, Zarantonello G, Messina A, Bozzi Y, Bernier R, Zucchelli S, Casarosa S, Dassi E, Ronzitti G, Golzio C, Morandell J, Gustincich S, Espinoza S, Biagioli M. Di Leva F, et al. Among authors: biagioli m. Mol Ther. 2024 Dec 30:S1525-0016(24)00843-8. doi: 10.1016/j.ymthe.2024.12.043. Online ahead of print. Mol Ther. 2024. PMID: 39741407 Free article.
Microbial-derived bile acid reverses inflammation in IBD via GPBAR1 agonism and RORγt inverse agonism.
Biagioli M, Di Giorgio C, Massa C, Marchianò S, Bellini R, Bordoni M, Urbani G, Roselli R, Lachi G, Morretta E, Piaz FD, Charlier B, Fiorillo B, Catalanotti B, Cari L, Nocentini G, Ricci P, Distrutti E, Festa C, Sepe V, Zampella A, Monti MC, Fiorucci S. Biagioli M, et al. Biomed Pharmacother. 2024 Dec;181:117731. doi: 10.1016/j.biopha.2024.117731. Epub 2024 Dec 9. Biomed Pharmacother. 2024. PMID: 39657506 Free article.
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
Rapacciuolo P, Finamore C, Giorgio CD, Fiorillo B, Massa C, Urbani G, Marchianò S, Bordoni M, Cassiano C, Morretta E, Spinelli L, Lupia A, Moraca F, Biagioli M, Sepe V, Monti MC, Catalanotti B, Fiorucci S, Zampella A. Rapacciuolo P, et al. Among authors: biagioli m. J Med Chem. 2024 Oct 24;67(20):18334-18355. doi: 10.1021/acs.jmedchem.4c01651. Epub 2024 Oct 9. J Med Chem. 2024. PMID: 39382988
Immunology of bile acids regulated receptors.
Fiorucci S, Marchianò S, Urbani G, Di Giorgio C, Distrutti E, Zampella A, Biagioli M. Fiorucci S, et al. Among authors: biagioli m. Prog Lipid Res. 2024 Jul;95:101291. doi: 10.1016/j.plipres.2024.101291. Epub 2024 Aug 8. Prog Lipid Res. 2024. PMID: 39122016 Review.
223 results