Kosai KI - Search Results

1

An optimal promoter regulating cytokine transgene expression is crucial for safe and effective oncolytic virus immunotherapy.

Kawakami H, Ijichi N, Obama Y, Matsuda E, Mitsui K, Nishikawaji Y, Watanabe M, Nagano S, Taniguchi N, Komiya S, Kosai KI. Kawakami H, et al. Among authors: kosai ki. Transl Res. 2024 Nov;273:32-45. doi: 10.1016/j.trsl.2024.07.002. Epub 2024 Jul 3. Transl Res. 2024. PMID: 38969167 Free article.

2

An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice.

Terazaki Y, Yano S, Yuge K, Nagano S, Fukunaga M, Guo ZS, Komiya S, Shirouzu K, Kosai K. Terazaki Y, et al. Hepatology. 2003 Jan;37(1):155-63. doi: 10.1053/jhep.2003.50018. Hepatology. 2003. PMID: 12500200

3

Gene therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only: novel concepts for successful cytokine gene therapy.

Nagano S, Yuge K, Fukunaga M, Terazaki Y, Fujiwara H, Komiya S, Kosai K. Nagano S, et al. Int J Oncol. 2004 Mar;24(3):549-58. Int J Oncol. 2004. PMID: 14767539

4

A definitive role of RhoC in metastasis of orthotopic lung cancer in mice.

Ikoma T, Takahashi T, Nagano S, Li YM, Ohno Y, Ando K, Fujiwara T, Fujiwara H, Kosai K. Ikoma T, et al. Clin Cancer Res. 2004 Feb 1;10(3):1192-200. doi: 10.1158/1078-0432.ccr-03-0275. Clin Cancer Res. 2004. PMID: 14871999 Free article.

5

Local overexpression of HB-EGF exacerbates remodeling following myocardial infarction by activating noncardiomyocytes.

Ushikoshi H, Takahashi T, Chen X, Khai NC, Esaki M, Goto K, Takemura G, Maruyama R, Minatoguchi S, Fujiwara T, Nagano S, Yuge K, Kawai T, Murofushi Y, Fujiwara H, Kosai K. Ushikoshi H, et al. Lab Invest. 2005 Jul;85(7):862-73. doi: 10.1038/labinvest.3700282. Lab Invest. 2005. PMID: 15856048 Free article.

6

An efficient construction of conditionally replicating adenoviruses that target tumor cells with multiple factors.

Nagano S, Oshika H, Fujiwara H, Komiya S, Kosai K. Nagano S, et al. Gene Ther. 2005 Sep;12(18):1385-93. doi: 10.1038/sj.gt.3302540. Gene Ther. 2005. PMID: 15877049

7

Adenoviral gene transduction of hepatocyte growth factor elicits inhibitory effects for hepatoma.

Yuge K, Takahashi T, Nagano S, Terazaki Y, Murofushi Y, Ushikoshi H, Kawai T, Khai NC, Nakamura T, Fujiwara H, Kosai K. Yuge K, et al. Int J Oncol. 2005 Jul;27(1):77-85. Int J Oncol. 2005. PMID: 15942646

8

Survivin-responsive conditionally replicating adenovirus exhibits cancer-specific and efficient viral replication.

Kamizono J, Nagano S, Murofushi Y, Komiya S, Fujiwara H, Matsuishi T, Kosai K. Kamizono J, et al. Cancer Res. 2005 Jun 15;65(12):5284-91. doi: 10.1158/0008-5472.CAN-04-2657. Cancer Res. 2005. PMID: 15958575

9

In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: a comparative study to HGF.

Khai NC, Takahashi T, Ushikoshi H, Nagano S, Yuge K, Esaki M, Kawai T, Goto K, Murofushi Y, Fujiwara T, Fujiwara H, Kosai K. Khai NC, et al. J Hepatol. 2006 Jun;44(6):1046-54. doi: 10.1016/j.jhep.2005.10.027. Epub 2005 Dec 7. J Hepatol. 2006. PMID: 16466829 Free article.

10

Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy.

Murofushi Y, Nagano S, Kamizono J, Takahashi T, Fujiwara H, Komiya S, Matsuishi T, Kosai K. Murofushi Y, et al. Int J Oncol. 2006 Sep;29(3):681-8. Int J Oncol. 2006. PMID: 16865285

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