Ambrus A - Search Results

1

Mitochondrial Alpha-Keto Acid Dehydrogenase Complexes: Recent Developments on Structure and Function in Health and Disease.

Szabo E, Nagy B, Czajlik A, Komlodi T, Ozohanics O, Tretter L, Ambrus A. Szabo E, et al. Among authors: ambrus a. Subcell Biochem. 2024;104:295-381. doi: 10.1007/978-3-031-58843-3_13. Subcell Biochem. 2024. PMID: 38963492 Review.

2

Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure.

Nagy B, Polak M, Ozohanics O, Zambo Z, Szabo E, Hubert A, Jordan F, Novaček J, Adam-Vizi V, Ambrus A. Nagy B, et al. Among authors: ambrus a. Biochim Biophys Acta Gen Subj. 2021 Jun;1865(6):129889. doi: 10.1016/j.bbagen.2021.129889. Epub 2021 Mar 5. Biochim Biophys Acta Gen Subj. 2021. PMID: 33684457 Free article.

3

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.

Ambrus A, Tretter L, Adam-Vizi V. Ambrus A, et al. J Neurochem. 2009 May;109 Suppl 1:222-9. doi: 10.1111/j.1471-4159.2009.05942.x. J Neurochem. 2009. PMID: 19393031 Free article.

4

Measurement of ROS homeostasis in isolated mitochondria.

Tretter L, Ambrus A. Tretter L, et al. Among authors: ambrus a. Methods Enzymol. 2014;547:199-223. doi: 10.1016/B978-0-12-801415-8.00012-6. Methods Enzymol. 2014. PMID: 25416360

5

Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components.

Ambrus A, Nemeria NS, Torocsik B, Tretter L, Nilsson M, Jordan F, Adam-Vizi V. Ambrus A, et al. Free Radic Biol Med. 2015 Dec;89:642-50. doi: 10.1016/j.freeradbiomed.2015.10.001. Epub 2015 Oct 9. Free Radic Biol Med. 2015. PMID: 26456061 Free PMC article.

6

Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism.

Zhang X, Nemeria NS, Leandro J, Houten S, Lazarus M, Gerfen G, Ozohanics O, Ambrus A, Nagy B, Brukh R, Jordan F. Zhang X, et al. Among authors: ambrus a. J Biol Chem. 2020 Jun 5;295(23):8078-8095. doi: 10.1074/jbc.RA120.012761. Epub 2020 Apr 17. J Biol Chem. 2020. PMID: 32303640 Free PMC article.

7

Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes.

Ozohanics O, Ambrus A. Ozohanics O, et al. Among authors: ambrus a. Life (Basel). 2020 Nov 15;10(11):286. doi: 10.3390/life10110286. Life (Basel). 2020. PMID: 33203161 Free PMC article. Review.

8

Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid.

Nemeria NS, Nagy B, Sanchez R, Zhang X, Leandro J, Ambrus A, Houten SM, Jordan F. Nemeria NS, et al. Among authors: ambrus a. Int J Mol Sci. 2022 Jul 26;23(15):8213. doi: 10.3390/ijms23158213. Int J Mol Sci. 2022. PMID: 35897808 Free PMC article.

9

Lipoamide dehydrogenase (LADH) deficiency: medical perspectives of the structural and functional characterization of LADH and its pathogenic variants.

Szabó E, Ambrus A. Szabó E, et al. Among authors: ambrus a. Biol Futur. 2023 Jun;74(1-2):109-118. doi: 10.1007/s42977-023-00155-6. Epub 2023 Feb 26. Biol Futur. 2023. PMID: 36842090 Review.

10

Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation.

Ozohanics O, Zhang X, Nemeria NS, Ambrus A, Jordan F. Ozohanics O, et al. Among authors: ambrus a. Int J Mol Sci. 2023 Feb 25;24(5):4555. doi: 10.3390/ijms24054555. Int J Mol Sci. 2023. PMID: 36901986 Free PMC article.

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