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Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients.
Gilmour N, Kern PS, Alépée N, Boislève F, Bury D, Clouet E, Hirota M, Hoffmann S, Kühnl J, Lalko JF, Mewes K, Miyazawa M, Nishida H, Osmani A, Petersohn D, Sekine S, van Vliet E, Klaric M. Gilmour N, et al. Among authors: kuhnl j. Regul Toxicol Pharmacol. 2020 Oct;116:104721. doi: 10.1016/j.yrtph.2020.104721. Epub 2020 Jul 6. Regul Toxicol Pharmacol. 2020. PMID: 32645429
Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model.
Kühnl J, Tao TP, Brandmair K, Gerlach S, Rings T, Müller-Vieira U, Przibilla J, Genies C, Jaques-Jamin C, Schepky A, Marx U, Hewitt NJ, Maschmeyer I. Kühnl J, et al. Toxicology. 2021 Jan 30;448:152637. doi: 10.1016/j.tox.2020.152637. Epub 2020 Nov 18. Toxicology. 2021. PMID: 33220337
Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under consumer-relevant conditions.
Tao TP, Maschmeyer I, LeCluyse EL, Rogers E, Brandmair K, Gerlach S, Przibilla J, Kern F, Genies C, Jacques C, Najjar A, Schepky A, Marx U, Kühnl J, Hewitt NJ. Tao TP, et al. Among authors: kuhnl j. Front Pharmacol. 2023 Feb 8;14:1076254. doi: 10.3389/fphar.2023.1076254. eCollection 2023. Front Pharmacol. 2023. PMID: 36843954 Free PMC article.
Suitability of different reconstructed human skin models in the skin and liver Chip2 microphysiological model to investigate the kinetics and first-pass skin metabolism of the hair dye, 4-amino-2-hydroxytoluene.
Brandmair K, Tao TP, Gerlach S, Przibilla J, Schepky A, Marx U, Hewitt NJ, Kühnl J, Maschmeyer I. Brandmair K, et al. Among authors: kuhnl j. J Appl Toxicol. 2024 Mar;44(3):333-343. doi: 10.1002/jat.4542. Epub 2023 Sep 12. J Appl Toxicol. 2024. PMID: 37699698 Free article.
26 results