Clarke JD - Search Results

1

The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies.

Clarke JD, Douangamath A, Mikolajek H, Bonnet-Di Placido M, Ren J, Fry EE, Stuart DI, Hammond JA, Owens RJ. Clarke JD, et al. Acta Crystallogr F Struct Biol Commun. 2024 Jul 1;80(Pt 7):154-163. doi: 10.1107/S2053230X2400606X. Epub 2024 Jul 1. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38958188 Free PMC article.

2

Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi.

Mikolajek H, Sanchez-Weatherby J, Sandy J, Gildea RJ, Campeotto I, Cheruvara H, Clarke JD, Foster T, Fujii S, Paulsen IT, Shah BS, Hough MA. Mikolajek H, et al. Among authors: clarke jd. IUCrJ. 2023 Jul 1;10(Pt 4):420-429. doi: 10.1107/S2052252523003810. IUCrJ. 2023. PMID: 37199504 Free PMC article.

3

Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.

Cornish K, Huo J, Jones L, Sharma P, Thrush JW, Abdelkarim S, Kipar A, Ramadurai S, Weckener M, Mikolajek H, Liu S, Buckle I, Bentley E, Kirby A, Han X, Laidlaw SM, Hill M, Eyssen L, Norman C, Le Bas A, Clarke J, James W, Stewart JP, Carroll M, Naismith JH, Owens RJ. Cornish K, et al. Open Biol. 2024 Jun;14(6):230252. doi: 10.1098/rsob.230252. Epub 2024 Jun 4. Open Biol. 2024. PMID: 38835241 Free PMC article.

4

A broadly reactive ultralong bovine antibody that can determine the integrity of foot-and-mouth disease virus capsids.

Clarke JD, Duyvesteyn HME, Perez-Martin E, Latišenko U, Porta C, Humphreys KV, Hay AL, Ren J, Fry EE, van den Born E, Charleston B, Bonnet-Di Placido M, Owens RJ, Stuart DI, Hammond JA. Clarke JD, et al. J Gen Virol. 2024 Oct;105(10):002032. doi: 10.1099/jgv.0.002032. J Gen Virol. 2024. PMID: 39422666 Free PMC article.

5

Coaching inexperienced clinicians before a high stakes medical procedure: randomized clinical trial.

Flynn SG, Park RS, Jena AB, Staffa SJ, Kim SY, Clarke JD, Pham IV, Lukovits KE, Huang SX, Sideridis GD, Bernier RS, Fiadjoe JE, Weinstock PH, Peyton JM, Stein ML, Kovatsis PG. Flynn SG, et al. Among authors: clarke jd. BMJ. 2024 Dec 16;387:e080924. doi: 10.1136/bmj-2024-080924. BMJ. 2024. PMID: 39681397 Free PMC article. Clinical Trial.

6

Microcystin-LR activates serine/threonine kinases and alters the phosphoproteome in human HepaRG cells.

Ikumawoyi VO, Lynch KD, Iverson DT, Call MR, Yue GE, Prasad B, Clarke JD. Ikumawoyi VO, et al. Among authors: clarke jd. Toxicon. 2024 Oct;249:108072. doi: 10.1016/j.toxicon.2024.108072. Epub 2024 Aug 20. Toxicon. 2024. PMID: 39154757

7

Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure.

Caldwell JL, Clarke JD, Smith CER, Pinali C, Quinn CJ, Pearman CM, Adomaviciene A, Radcliffe EJ, Watkins A, Horn MA, Bode EF, Madders GWP, Eisner M, Eisner DA, Trafford AW, Dibb KM. Caldwell JL, et al. Among authors: clarke jd. Circ Res. 2024 Sep 13;135(7):739-754. doi: 10.1161/CIRCRESAHA.124.324601. Epub 2024 Aug 14. Circ Res. 2024. PMID: 39140440 Free PMC article.

8

Mechanisms of intestinal pharmacokinetic natural product-drug interactions.

Oyanna VO, Clarke JD. Oyanna VO, et al. Among authors: clarke jd. Drug Metab Rev. 2024 Aug;56(3):285-301. doi: 10.1080/03602532.2024.2386597. Epub 2024 Aug 12. Drug Metab Rev. 2024. PMID: 39078118 Review.

9

Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model.

Bechtold BJ, Lynch KD, Oyanna VO, Call MR, Graf TN, Oberlies NH, Clarke JD. Bechtold BJ, et al. Among authors: clarke jd. Mol Pharm. 2024 May 6;21(5):2284-2297. doi: 10.1021/acs.molpharmaceut.3c01088. Epub 2024 Mar 26. Mol Pharm. 2024. PMID: 38529622

10

Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.

Bechtold BJ, Lynch KD, Oyanna VO, Call MR, White LA, Graf TN, Oberlies NH, Clarke JD. Bechtold BJ, et al. Among authors: clarke jd. Drug Metab Dispos. 2024 Apr 16;52(5):355-367. doi: 10.1124/dmd.123.001607. Drug Metab Dispos. 2024. PMID: 38485280 Free PMC article.

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