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Sex and aging signatures of proteomics in human cerebrospinal fluid identify distinct clusters linked to neurodegeneration.
Seo D, Lee CM, Apio C, Heo G, Timsina J, Kohlfeld P, Boada M, Orellana A, Fernandez MV, Ruiz A, Morris JC, Schindler SE, Park T, Cruchaga C, Sung YJ. Seo D, et al. Among authors: orellana a. medRxiv [Preprint]. 2024 Jun 19:2024.06.18.24309102. doi: 10.1101/2024.06.18.24309102. medRxiv. 2024. PMID: 38947020 Free PMC article. Preprint.
Connecting genomic and proteomic signatures of amyloid burden in the brain.
Puerta R, de Rojas I, García-González P, Olivé C, Sotolongo-Grau O, García-Sánchez A, García-Gutiérrez F, Montrreal L, Pablo Tartari J, Sanabria Á, Pytel V, Lage C, Quintela I, Aguilera N, Rodriguez-Rodriguez E, Alarcón-Martín E, Orellana A, Pastor P, Pérez-Tur J, Piñol-Ripoll G, de Munian AL, García-Alberca JM, Royo JL, Bullido MJ, Álvarez V, Real LM, Anchuelo AC, Gómez-Garre D, Larrad MTM, Franco-Macías E, Mir P, Medina M, Sánchez-Valle R, Dols-Icardo O, Sáez ME, Carracedo Á, Tárraga L, Alegret M, Valero S, Marquié M, Boada M, Juan PS, Cavazos JE, Cabrera A, Cano A; Alzheimer’s Disease Neuroimaging Initiative.. Puerta R, et al. Among authors: orellana a. medRxiv [Preprint]. 2024 Sep 6:2024.09.06.24313124. doi: 10.1101/2024.09.06.24313124. medRxiv. 2024. PMID: 39281766 Free PMC article. Preprint.
Macular vessel density in the superficial plexus is not a proxy of cerebrovascular damage in non-demented individuals: data from the NORFACE cohort.
García-Sánchez A, Sotolongo-Grau O, Tartari JP, Sanabria Á, Esteban-De Antonio E, Pérez-Cordón A, Alegret M, Pytel V, Martínez J, Aguilera N, de Rojas I, Cano A, García-González P, Puerta R, Olivé C, Capdevila M, García-Gutiérrez F, Vivas A, Gómez-Chiari M, Giménez J, Tejero MÁ, Castilla-Martí M, Castilla-Martí L, Tárraga L, Valero S, Ruiz A, Boada M, Marquié M; FACEHBI study group; BIOFACE study group. García-Sánchez A, et al. Alzheimers Res Ther. 2024 Feb 20;16(1):42. doi: 10.1186/s13195-024-01408-9. Alzheimers Res Ther. 2024. PMID: 38378643 Free PMC article.
Exploring APOE genotype effects on Alzheimer's disease risk and amyloid β burden in individuals with subjective cognitive decline: The FundacioACE Healthy Brain Initiative (FACEHBI) study baseline results.
Moreno-Grau S, Rodríguez-Gómez O, Sanabria Á, Pérez-Cordón A, Sánchez-Ruiz D, Abdelnour C, Valero S, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Gil S, Santos-Santos MÁ, Alegret M, Espinosa A, Ortega G, Guitart M, Gailhajanet A, de Rojas I, Sotolongo-Grau Ó, Ruiz S, Aguilera N, Papasey J, Martín E, Peleja E; Alzheimer's Disease Neuroimaging Initiative; Lomeña F, Campos F, Vivas A, Gómez-Chiari M, Tejero MÁ, Giménez J, Serrano-Ríos M, Orellana A, Tárraga L, Ruiz A, Boada M; FACEHBI study group. Moreno-Grau S, et al. Among authors: orellana a. Alzheimers Dement. 2018 May;14(5):634-643. doi: 10.1016/j.jalz.2017.10.005. Epub 2017 Nov 20. Alzheimers Dement. 2018. PMID: 29156223 Free article.
Head-to-Head Comparison of Aptamer- and Antibody-Based Proteomic Platforms in Human Cerebrospinal Fluid Samples from a Real-World Memory Clinic Cohort.
Puerta R, Cano A, García-González P, García-Gutiérrez F, Capdevila M, de Rojas I, Olivé C, Blázquez-Folch J, Sotolongo-Grau O, Miguel A, Montrreal L, Martino-Adami P, Khan A, Orellana A, Sung YJ, Frikke-Schmidt R, Marchant N, Lambert JC, Rosende-Roca M, Alegret M, Fernández MV, Marquié M, Valero S, Tárraga L, Cruchaga C, Ramírez A, Boada M, Smets B, Cabrera-Socorro A, Ruiz A. Puerta R, et al. Among authors: orellana a. Int J Mol Sci. 2024 Dec 31;26(1):286. doi: 10.3390/ijms26010286. Int J Mol Sci. 2024. PMID: 39796148 Free PMC article.
Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia.
Morató X, Puerta R, Cano A, Orellana A, de Rojas I, Capdevila M, Montrreal L, Rosende-Roca M, García-González P, Olivé C, García-Gutiérrez F, Blázquez J, Miguel A, Núñez-Llaves R, Pytel V, Alegret M, Fernández MV, Marquié M, Valero S, Cavazos JE, Mañes S, Boada M, Cabrera-Socorro A, Ruiz A. Morató X, et al. Among authors: orellana a. Brain Behav Immun Health. 2024 Nov 16;42:100899. doi: 10.1016/j.bbih.2024.100899. eCollection 2024 Dec. Brain Behav Immun Health. 2024. PMID: 39640195 Free PMC article.
Head-to-head comparison of tau PET tracers [18F]PI-2620 and [18F]RO948 in non-demented individuals with brain amyloid deposition: the TAU-PET FACEHBI cohort.
Tonietto M, Sotolongo-Grau O, Roé-Vellvé N, Bullich S, Tartari JP, Sanabria Á, García-Sánchez A, Borroni E, Galli C, Pérez-Martínez E, Castell-Conesa J, Roca I, Tárraga L, Ruiz A, Stephens AW, Boada M, Klein G, Marquié M; FACEHBI study group; AMYPAD consortium. Tonietto M, et al. Alzheimers Res Ther. 2024 Nov 28;16(1):257. doi: 10.1186/s13195-024-01622-5. Alzheimers Res Ther. 2024. PMID: 39605030 Free PMC article.
Amyloid deposition in adults with drug-resistant temporal lobe epilepsy.
Fonseca E, Lallana S, Ortega G, Cano A, Sarria-Estrada S, Pareto D, Quintana M, Lorenzo-Bosquet C, López-Maza S, Gifreu A, Campos-Fernández D, Abraira L, Santamarina E, Orellana A, Montrreal L, Puerta R, Aguilera N, Ramis M, de Rojas I, Ruiz A, Tárraga L, Rovira À, Marquié M, Boada M, Toledo M. Fonseca E, et al. Among authors: orellana a. Epilepsia. 2024 Dec;65(12):3664-3675. doi: 10.1111/epi.18142. Epub 2024 Oct 15. Epilepsia. 2024. PMID: 39403981
Clinical value of plasma pTau181 to predict Alzheimer's disease pathology in a large real-world cohort of a memory clinic.
Cano A, Capdevila M, Puerta R, Arranz J, Montrreal L, de Rojas I, García-González P, Olivé C, García-Gutiérrez F, Sotolongo-Grau O, Orellana A, Aguilera N, Ramis M, Rosende-Roca M, Lleó A, Fortea J, Tartari JP, Lafuente A, Vargas L, Pérez-Cordón A, Muñoz N, Sanabria Á, Alegret M, Morató X, Tárraga L, Fernández V, Marquié M, Valero S, Alcolea D, Boada M, Ruiz A. Cano A, et al. Among authors: orellana a. EBioMedicine. 2024 Oct;108:105345. doi: 10.1016/j.ebiom.2024.105345. Epub 2024 Sep 18. EBioMedicine. 2024. PMID: 39299003 Free PMC article.
Association of oxidative stress and inflammatory metabolites with Alzheimer's disease cerebrospinal fluid biomarkers in mild cognitive impairment.
Ahmad S, Yang W, Orellana A, Frölich L, de Rojas I, Cano A, Boada M, Hernández I, Hausner L, Harms AC, Bakker MHM, Cabrera-Socorro A, Amin N, Ramírez A, Ruiz A, Van Duijn CM, Hankemeier T. Ahmad S, et al. Among authors: orellana a. Alzheimers Res Ther. 2024 Jul 30;16(1):171. doi: 10.1186/s13195-024-01542-4. Alzheimers Res Ther. 2024. PMID: 39080778 Free PMC article.
233 results