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Page 1
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research.
Ibanez L, Liu M, Beric A, Timsina J, Kohlfeld P, Bergmann K, Lowery J, Sykora N, Sanchez-Montejo B, Brock W, Budde JP, Bateman RJ, Barthelemy N, Schindler SE, Holtzman DM, Benzinger TLS, Xiong C, Tarawneh R, Moulder K, Morris JC, Sung YJ, Cruchaga C. Ibanez L, et al. Among authors: kohlfeld p. Alzheimers Dement. 2024 Nov 22. doi: 10.1002/alz.14413. Online ahead of print. Alzheimers Dement. 2024. PMID: 39575871
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.
Western D, Timsina J, Wang L, Wang C, Yang C, Phillips B, Wang Y, Liu M, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey AI, Morris JC, Perrin RJ, Ruiz A, Marquié M, Boada M, de Rojas I, Rutledge J, Oh H, Wilson EN, Le Guen Y, Reus LM, Tijms B, Visser PJ, van der Lee SJ, Pijnenburg YAL, Teunissen CE, Del Campo Milan M, Alvarez I, Aguilar M; Dominantly Inherited Alzheimer Network (DIAN); Alzheimer’s Disease Neuroimaging Initiative (ADNI); Greicius MD, Pastor P, Pulford DJ, Ibanez L, Wyss-Coray T, Sung YJ, Cruchaga C. Western D, et al. Among authors: kohlfeld p. Nat Genet. 2024 Dec;56(12):2672-2684. doi: 10.1038/s41588-024-01972-8. Epub 2024 Nov 11. Nat Genet. 2024. PMID: 39528825
Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center.
Fernandez MV, Liu M, Beric A, Johnson M, Cetin A, Patel M, Budde J, Kohlfeld P, Bergmann K, Lowery J, Flynn A, Brock W, Sanchez Montejo B, Gentsch J, Sykora N, Norton J, Gentsch J, Valdez O, Gorijala P, Sanford J, Sun Y, Wang C, Western D, Timsina J, Mangetti Goncalves T, Do AN, Sung YJ, Zhao G, Morris JC, Moulder K, Holtzman DM, Bateman RJ, Karch C, Hassenstab J, Xiong C, Schindler SE, Balls-Berry JJ, Benzinger TLS, Perrin RJ, Denny A, Snider BJ, Stark SL, Ibanez L, Cruchaga C. Fernandez MV, et al. Among authors: kohlfeld p. Sci Data. 2024 Jul 12;11(1):768. doi: 10.1038/s41597-024-03485-9. Sci Data. 2024. PMID: 38997326 Free PMC article.
Sex and aging signatures of proteomics in human cerebrospinal fluid identify distinct clusters linked to neurodegeneration.
Seo D, Lee CM, Apio C, Heo G, Timsina J, Kohlfeld P, Boada M, Orellana A, Fernandez MV, Ruiz A, Morris JC, Schindler SE, Park T, Cruchaga C, Sung YJ. Seo D, et al. Among authors: kohlfeld p. medRxiv [Preprint]. 2024 Jun 19:2024.06.18.24309102. doi: 10.1101/2024.06.18.24309102. medRxiv. 2024. PMID: 38947020 Free PMC article. Preprint.
Organ aging signatures in the plasma proteome track health and disease.
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Oh HS, et al. Among authors: kohlfeld p. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6. Nature. 2023. PMID: 38057571 Free PMC article.
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease.
Cruchaga C, Western D, Timsina J, Wang L, Wang C, Yang C, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey A, Morris J, Perrin R, Ruiz A, Marquié M, Boada M, de Rojas I, Rutledge J, Oh H, Wilson E, Guen YL, Alvarez I, Aguilar M, Greicius M, Pastor P, Pulford D, Ibanez L, Wyss-Coray T, Sung YJ, Phillips B. Cruchaga C, et al. Among authors: kohlfeld p. Res Sq [Preprint]. 2023 Jun 9:rs.3.rs-2814616. doi: 10.21203/rs.3.rs-2814616/v1. Res Sq. 2023. Update in: Nat Genet. 2024 Dec;56(12):2672-2684. doi: 10.1038/s41588-024-01972-8 PMID: 37333337 Free PMC article. Updated. Preprint.
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer's and coronary disease pathways.
Wang L, Western D, Timsina J, Repaci C, Song WM, Norton J, Kohlfeld P, Budde J, Climer S, Butt OH, Jacobson D, Garvin M, Templeton AR, Campagna S, O'Halloran J, Presti R, Goss CW, Mudd PA, Ances BM, Zhang B, Sung YJ, Cruchaga C. Wang L, et al. Among authors: kohlfeld p. iScience. 2023 Apr 21;26(4):106408. doi: 10.1016/j.isci.2023.106408. Epub 2023 Mar 14. iScience. 2023. PMID: 36974157 Free PMC article.
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer and coronary disease pathways.
Wang L, Western D, Timsina J, Repaci C, Song WM, Norton J, Kohlfeld P, Budde J, Climer S, Butt OH, Jacobson D, Garvin M, Templeton AR, Campagna S, O'Halloran J, Presti R, Goss CW, Mudd PA, Ances BM, Zhang B, Sung YJ, Cruchaga C. Wang L, et al. Among authors: kohlfeld p. medRxiv [Preprint]. 2022 Jul 25:2022.07.25.22278025. doi: 10.1101/2022.07.25.22278025. medRxiv. 2022. Update in: iScience. 2023 Apr 21;26(4):106408. doi: 10.1016/j.isci.2023.106408 PMID: 35923315 Free PMC article. Updated. Preprint.