Chen Q - Search Results

1

Novel OX40 and 4-1BB derived spacers enhance CD30 CAR activity and safety in CD30 positive lymphoma models.

Kua L, Ng CH, Tan JW, Tan HC, Seh CC, Wong F, Ong R, Rooney CM, Tan J, Chen Q, Horak ID, Tan KW, Low L. Kua L, et al. Among authors: chen q. Mol Ther. 2024 Oct 2;32(10):3504-3521. doi: 10.1016/j.ymthe.2024.06.037. Epub 2024 Jun 29. Mol Ther. 2024. PMID: 38946142

2

Towards a better preclinical cancer model - human immune aging in humanized mice.

Tan JHL, Hwang YY, Chin HX, Liu M, Tan SY, Chen Q. Tan JHL, et al. Among authors: chen q. Immun Ageing. 2023 Sep 27;20(1):49. doi: 10.1186/s12979-023-00374-4. Immun Ageing. 2023. PMID: 37752597 Free PMC article.

3

B7-H3-Targeting Chimeric Antigen Receptors Epstein-Barr Virus-specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3-positive Solid Tumors.

Yeo SP, Kua L, Tan JW, Lim JK, Wong FH, Santos MD, Poh CM, Goh AX, Koh XY, Zhou X, Rajarethinam R, Chen Q, Her Z, Horak ID, Low L, Tan KW. Yeo SP, et al. Among authors: chen q. Cancer Res Commun. 2024 Jun 4;4(6):1410-1429. doi: 10.1158/2767-9764.CRC-23-0538. Cancer Res Commun. 2024. PMID: 38717140 Free PMC article.

4

A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells.

Sin WX, Jagannathan NS, Teo DBL, Kairi F, Fong SY, Tan JHL, Sandikin D, Cheung KW, Luah YH, Wu X, Raymond JJ, Lim FLWI, Lee YH, Seng MS, Soh SY, Chen Q, Ram RJ, Tucker-Kellogg L, Birnbaum ME. Sin WX, et al. Among authors: chen q. Nat Biomed Eng. 2024 Dec;8(12):1571-1591. doi: 10.1038/s41551-024-01219-1. Epub 2024 Jun 4. Nat Biomed Eng. 2024. PMID: 38834752

5

Single-cell RNA sequencing reveals anti-tumor potency of CD56⁺ NK cells and CD8⁺ T cells in humanized mice via PD-1 and TIGIT co-targeting.

Liu WN, Harden SL, Tan SLW, Tan RJR, Fong SY, Tan SY, Liu M, Karnik I, Shuen TWH, Toh HC, Fan Y, Lim SG, Chan JKY, Chen Q. Liu WN, et al. Among authors: chen q. Mol Ther. 2024 Nov 6;32(11):3895-3914. doi: 10.1016/j.ymthe.2024.09.025. Epub 2024 Sep 23. Mol Ther. 2024. PMID: 39318093 Free PMC article.

6

Cell Granularity Reflects Immune Cell Function and Enables Selection of Lymphocytes with Superior Attributes for Immunotherapy.

Wu T, Tan JHL, Sin WX, Luah YH, Tan SY, Goh M, Birnbaum ME, Chen Q, Cheow LF. Wu T, et al. Among authors: chen q. Adv Sci (Weinh). 2023 Oct;10(28):e2302175. doi: 10.1002/advs.202302175. Epub 2023 Aug 6. Adv Sci (Weinh). 2023. PMID: 37544893 Free PMC article.

7

Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma.

Ang DA, Carter JM, Deka K, Tan JHL, Zhou J, Chen Q, Chng WJ, Harmston N, Li Y. Ang DA, et al. Among authors: chen q. Nat Commun. 2024 Mar 21;15(1):2513. doi: 10.1038/s41467-024-46728-4. Nat Commun. 2024. PMID: 38514625 Free PMC article.

8

CD4⁺ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice.

Her Z, Tan JHL, Lim YS, Tan SY, Chan XY, Tan WWS, Liu M, Yong KSM, Lai F, Ceccarello E, Zheng Z, Fan Y, Chang KTE, Sun L, Chang SC, Chin CL, Lee GH, Dan YY, Chan YS, Lim SG, Chan JKY, Chandy KG, Chen Q. Her Z, et al. Among authors: chen q. Front Immunol. 2020 Sep 11;11:580968. doi: 10.3389/fimmu.2020.580968. eCollection 2020. Front Immunol. 2020. PMID: 33013934 Free PMC article.

9

Preclinical Activity of Embryonic Annexin A2-Specific Chimeric Antigen Receptor T Cells Against Ovarian Cancer.

Leong L, Tan HL, Cua S, Yong KSM, Chen Q, Choo A. Leong L, et al. Among authors: chen q. Int J Mol Sci. 2020 Jan 7;21(2):381. doi: 10.3390/ijms21020381. Int J Mol Sci. 2020. PMID: 31936170 Free PMC article.

10

IL12/18/21 Preactivation Enhances the Antitumor Efficacy of Expanded γδT Cells and Overcomes Resistance to Anti-PD-L1 Treatment.

Teo HY, Song Y, Yong KSM, Liu Y, Mei Y, Hanafi ZB, Zhu Y, Chua YL, Gascoigne NRJ, Chen Q, Liu H. Teo HY, et al. Among authors: chen q. Cancer Immunol Res. 2023 Jul 5;11(7):978-999. doi: 10.1158/2326-6066.CIR-21-0952. Cancer Immunol Res. 2023. PMID: 37099651

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