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Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity.
Iida T, Itoh Y, Takahashi Y, Miyake Y, Zamani F, Yamashita Y, Takada Y, Akiyama T, Ibaraki J, Okuda K, Tokuda Y, Nishimura T, Hidaka K, Mori H, Oba M, Suzuki T. Iida T, et al. Among authors: takahashi y. Chem Pharm Bull (Tokyo). 2024;72(7):638-647. doi: 10.1248/cpb.c23-00026. Chem Pharm Bull (Tokyo). 2024. PMID: 38945940 Free article.
Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.
Mellini P, Itoh Y, Elboray EE, Tsumoto H, Li Y, Suzuki M, Takahashi Y, Tojo T, Kurohara T, Miyake Y, Miura Y, Kitao Y, Kotoku M, Iida T, Suzuki T. Mellini P, et al. Among authors: takahashi y. J Med Chem. 2019 Jun 27;62(12):5844-5862. doi: 10.1021/acs.jmedchem.9b00255. Epub 2019 Jun 12. J Med Chem. 2019. PMID: 31144814
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach.
Prakash M, Itoh Y, Fujiwara Y, Takahashi Y, Takada Y, Mellini P, Elboray EE, Terao M, Yamashita Y, Yamamoto C, Yamaguchi T, Kotoku M, Kitao Y, Singh R, Roy R, Obika S, Oba M, Wang DO, Suzuki T. Prakash M, et al. Among authors: takahashi y. J Med Chem. 2021 Nov 11;64(21):15810-15824. doi: 10.1021/acs.jmedchem.1c01107. Epub 2021 Nov 3. J Med Chem. 2021. PMID: 34727689
Triple mosaic variants of PURA in a patient with multiple congenital anomalies.
Fujita A, Suenaga Y, Takeshita E, Takahashi Y, Suzuki Y, Ohori S, Tsuchida N, Uchiyama Y, Koshimizu E, Miyatake S, Mizuguchi T, Matsumoto N. Fujita A, et al. Among authors: takahashi y. J Hum Genet. 2025 Jan 14. doi: 10.1038/s10038-024-01315-9. Online ahead of print. J Hum Genet. 2025. PMID: 39809889
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