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Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells.
McCracken IR, Saginc G, He L, Huseynov A, Daniels A, Fletcher S, Peghaire C, Kalna V, Andaloussi-Mäe M, Muhl L, Craig NM, Griffiths SJ, Haas JG, Tait-Burkard C, Lendahl U, Birdsey GM, Betsholtz C, Noseda M, Baker AH, Randi AM. McCracken IR, et al. Among authors: fletcher s. Circulation. 2021 Feb 23;143(8):865-868. doi: 10.1161/CIRCULATIONAHA.120.052824. Epub 2021 Jan 6. Circulation. 2021. PMID: 33405941 Free PMC article. No abstract available.
Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions.
Meek S, Watson T, Eory L, McFarlane G, Wynne FJ, McCleary S, Dunn LEM, Charlton EM, Craig C, Shih B, Regan T, Taylor R, Sutherland L, Gossner A, Chintoan-Uta C, Fletcher S, Beard PM, Hassan MA, Grey F, Hope JC, Stevens MP, Nowak-Imialek M, Niemann H, Ross PJ, Tait-Burkard C, Brown SM, Lefevre L, Thomson G, McColl BW, Lawrence AB, Archibald AL, Steinbach F, Crooke HR, Gao X, Liu P, Burdon T. Meek S, et al. Among authors: fletcher s. BMC Biol. 2022 Jan 14;20(1):14. doi: 10.1186/s12915-021-01217-8. BMC Biol. 2022. PMID: 35027054 Free PMC article.
Differential RNA editing landscapes in host cell versus the SARS-CoV-2 genome.
Kurkowiak M, Fletcher S, Daniels A, Mozolewski P, Silvestris DA, Król E, Marek-Trzonkowska N, Hupp T, Tait-Burkard C. Kurkowiak M, et al. Among authors: fletcher s. iScience. 2023 Sep 30;26(11):108031. doi: 10.1016/j.isci.2023.108031. eCollection 2023 Nov 17. iScience. 2023. PMID: 37876814 Free PMC article.
Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.
Chau LF, Lillico S, Opriessnig T, Blake R, Tardy L, Lee CH, Maxwell S, Warren C, Thornton E, Mclaughlin CL, McLachlan G, Tait-Burkard C, Fletcher S, Anderson S, Brown S, Gibbard L, Tzelos T, MacMillan-Christensen D, Baillie JK, Dorward DA, Griffiths DJ, Grey F. Chau LF, et al. Among authors: fletcher s. Nat Commun. 2025 Jan 17;16(1):766. doi: 10.1038/s41467-024-54615-1. Nat Commun. 2025. PMID: 39824810 Free PMC article.
Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort study.
Gharibzadeh S, Routen A, Razieh C, Zaccardi F, Lawson C, Gillies C, Heller S, Davies M, Atkins H, Bain SC, Lone NL, Poinasamy K, Peto T, Robertson E, Young B, Johnston D, Quint J, Valabhji J, Ismail K, Marks M, Horsley A, Docherty A, Harrison E, Chalmers J, Ho LP, Raman B, Brightling C, Elneima O, Evans R, Greening N, Harris VC, Houchen-Wolloff L, Sereno M, Shikotra A, Singapuri A, Wain L, Langenberg C, Dennis J, Petrie J, Sattar N, Leavy O, Richardson M, Saunders RM, McArdle A, McASuley H, Yates T, Khunti K; PHOSP-COVID Study Collaborative Group. Gharibzadeh S, et al. EClinicalMedicine. 2024 Dec 27;79:103005. doi: 10.1016/j.eclinm.2024.103005. eCollection 2025 Jan. EClinicalMedicine. 2024. PMID: 39834716 Free PMC article.
The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN-GIL hybrid single-molecule inhibitors.
Goodis CC, Eberly C, Chan AM, Kim M, Lowe BD, Civin CI, Fletcher S. Goodis CC, et al. Among authors: fletcher s. Eur J Med Chem. 2024 Dec 22;285:117190. doi: 10.1016/j.ejmech.2024.117190. Online ahead of print. Eur J Med Chem. 2024. PMID: 39813774
1,533 results