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472 results

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SGLT2 Inhibitor Dapagliflozin Increases Skeletal Muscle and Brain Fatty Acid Uptake in Individuals With Type 2 Diabetes: A Randomized Double-Blind Placebo-Controlled Positron Emission Tomography Study.
Latva-Rasku A, Rebelos E, Tuisku J, Aarnio R, Bhowmik A, Keskinen H, Laurila S, Lahesmaa-Hatting M, Pekkarinen L, Isackson H, Kirjavainen AK, Koffert J, Heurling K, Nummenmaa L, Ferrannini E, Oldgren J, Oscarsson J, Nuutila P. Latva-Rasku A, et al. Among authors: nuutila p. Diabetes Care. 2024 Sep 1;47(9):1630-1637. doi: 10.2337/dc24-0470. Diabetes Care. 2024. PMID: 38941156 Clinical Trial.
The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients.
Latva-Rasku A, Honka MJ, Kullberg J, Mononen N, Lehtimäki T, Saltevo J, Kirjavainen AK, Saunavaara V, Iozzo P, Johansson L, Oscarsson J, Hannukainen JC, Nuutila P. Latva-Rasku A, et al. Among authors: nuutila p. Diabetes Care. 2019 May;42(5):931-937. doi: 10.2337/dc18-1569. Epub 2019 Mar 18. Diabetes Care. 2019. PMID: 30885955 Free article. Clinical Trial.
Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study.
Rebelos E, Hirvonen J, Bucci M, Pekkarinen L, Nyman M, Hannukainen JC, Iozzo P, Salminen P, Nummenmaa L, Ferrannini E, Nuutila P. Rebelos E, et al. Among authors: nuutila p. Diabetes Obes Metab. 2020 Jul;22(7):1074-1082. doi: 10.1111/dom.13996. Epub 2020 Feb 24. Diabetes Obes Metab. 2020. PMID: 32052537 Free PMC article.
Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort.
Rebelos E, Bucci M, Karjalainen T, Oikonen V, Bertoldo A, Hannukainen JC, Virtanen KA, Latva-Rasku A, Hirvonen J, Heinonen I, Parkkola R, Laakso M, Ferrannini E, Iozzo P, Nummenmaa L, Nuutila P. Rebelos E, et al. Among authors: nuutila p. Diabetes Care. 2021 Mar;44(3):788-794. doi: 10.2337/dc20-1549. Epub 2021 Jan 14. Diabetes Care. 2021. PMID: 33446523 Free PMC article.
Effects of 6 weeks of treatment with dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo-controlled, exploratory study.
Oldgren J, Laurila S, Åkerblom A, Latva-Rasku A, Rebelos E, Isackson H, Saarenhovi M, Eriksson O, Heurling K, Johansson E, Wilderäng U, Karlsson C, Esterline R, Ferrannini E, Oscarsson J, Nuutila P. Oldgren J, et al. Among authors: nuutila p. Diabetes Obes Metab. 2021 Jul;23(7):1505-1517. doi: 10.1111/dom.14363. Epub 2021 Mar 12. Diabetes Obes Metab. 2021. PMID: 33625777 Free article. Clinical Trial.
A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.
Latva-Rasku A, Honka MJ, Stančáková A, Koistinen HA, Kuusisto J, Guan L, Manning AK, Stringham H, Gloyn AL, Lindgren CM; T2D-GENES Consortium; Collins FS, Mohlke KL, Scott LJ, Karjalainen T, Nummenmaa L, Boehnke M, Nuutila P, Laakso M. Latva-Rasku A, et al. Among authors: nuutila p. Diabetes. 2018 Feb;67(2):334-342. doi: 10.2337/db17-1142. Epub 2017 Nov 15. Diabetes. 2018. PMID: 29141982 Free PMC article.
Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow-up.
Rebelos E, Immonen H, Bucci M, Hannukainen JC, Nummenmaa L, Honka MJ, Soinio M, Salminen P, Ferrannini E, Iozzo P, Nuutila P. Rebelos E, et al. Among authors: nuutila p. Diabetes Obes Metab. 2019 Feb;21(2):218-226. doi: 10.1111/dom.13501. Epub 2018 Sep 16. Diabetes Obes Metab. 2019. PMID: 30098134 Free PMC article. Clinical Trial.
Effects of DAPAgliflozin on CARDiac substrate uptake, myocardial efficiency, and myocardial contractile work in type 2 diabetes patients-a description of the DAPACARD study.
Åkerblom A, Oldgren J, Latva-Rasku A, Johansson L, Lisovskaja V, Karlsson C, Oscarsson J, Nuutila P. Åkerblom A, et al. Among authors: nuutila p. Ups J Med Sci. 2019 Jan;124(1):59-64. doi: 10.1080/03009734.2018.1515281. Epub 2019 Jan 8. Ups J Med Sci. 2019. PMID: 30618324 Free PMC article. Clinical Trial.
472 results