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Page 1
Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Thathy V, Hackett F, Yeo T, Li VL, Muir R, Faucher F, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: blackman mj. Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006. Epub 2024 Aug 12. Cell Chem Biol. 2024. PMID: 39137783
Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine.
Ward KE, Christensen P, Racklyeft A, Dhingra SK, Chua ACY, Remmert C, Suwanarusk R, Matheson J, Blackman MJ, Kaneko O, Kyle DE, Lee MCS, Moon RW, Snounou G, Rénia L, Fidock DA, Russell B, Bifani P. Ward KE, et al. Among authors: blackman mj. J Infect Dis. 2023 May 12;227(10):1121-1126. doi: 10.1093/infdis/jiac469. J Infect Dis. 2023. PMID: 36478252 Free PMC article.
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Hackett F, Yeo T, Li VL, Muir RK, Faucher FF, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: blackman mj. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575224. doi: 10.1101/2024.01.11.575224. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006 PMID: 38260474 Free PMC article. Updated. Preprint.
A patatin-like phospholipase is important for mitochondrial function in malaria parasites.
Pietsch E, Ramaprasad A, Bielfeld S, Wohlfarter Y, Maco B, Niedermüller K, Wilcke L, Kloehn J, Keller MA, Soldati-Favre D, Blackman MJ, Gilberger T-W, Burda P-C. Pietsch E, et al. Among authors: blackman mj. mBio. 2023 Dec 19;14(6):e0171823. doi: 10.1128/mbio.01718-23. Epub 2023 Oct 26. mBio. 2023. PMID: 37882543 Free PMC article.
Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity.
Kovada V, Withers-Martinez C, Bobrovs R, Ce Rule HN, Liepins E, Grinberga S, Hackett F, Collins CR, Kreicberga A, Jiménez-Díaz MB, Angulo-Barturen I, Rasina D, Suna E, Jaudzems K, Blackman MJ, Jirgensons A. Kovada V, et al. Among authors: blackman mj. J Med Chem. 2023 Aug 10;66(15):10658-10680. doi: 10.1021/acs.jmedchem.3c00812. Epub 2023 Jul 28. J Med Chem. 2023. PMID: 37505188 Free PMC article.
171 results