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Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase.
Palmer N, Agnew C, Benn C, Buffham WJ, Castro JN, Chessari G, Clark M, Cons BD, Coyle JE, Dawson LA, Hamlett CCF, Hodson C, Holding F, Johnson CN, Liebeschuetz JW, Mahajan P, McCarthy JM, Murray CW, O'Reilly M, Peakman T, Price A, Rapti M, Reeks J, Schöpf P, St-Denis JD, Valenzano C, Wallis NG, Walser R, Weir H, Wilsher NE, Woodhead A, Bento CF, Tisi D. Palmer N, et al. Among authors: agnew c. J Med Chem. 2024 Jul 11;67(13):11168-11181. doi: 10.1021/acs.jmedchem.4c00702. Epub 2024 Jun 27. J Med Chem. 2024. PMID: 38932616
Evaluation of tumour motion and internal/external correlation in lung SABR.
Ali AM, Greenwood JB, Walls GM, Belshaw L, Agnew CE, McAleese J, Whitten G, Irvine DM, Hounsell AR, McGarry CK. Ali AM, et al. Among authors: agnew ce. Br J Radiol. 2023 Sep;96(1149):20220461. doi: 10.1259/bjr.20220461. Epub 2023 Jul 10. Br J Radiol. 2023. PMID: 37393541 Free PMC article.
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.
Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. Lo M, et al. Among authors: agnew c. Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. Nat Commun. 2022. PMID: 35504891 Free PMC article.
Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.
Campbell MR, Ruiz-Saenz A, Peterson E, Agnew C, Ayaz P, Garfinkle S, Littlefield P, Steri V, Oeffinger J, Sampang M, Shan Y, Shaw DE, Jura N, Moasser MM. Campbell MR, et al. Among authors: agnew c. Cell Rep. 2022 Feb 1;38(5):110291. doi: 10.1016/j.celrep.2021.110291. Cell Rep. 2022. PMID: 35108525 Free PMC article.
138 results