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Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity.
Peters TL, Tillotson J, Yeomans AM, Wilmore S, Lemm E, Jiménez-Romero C, Amador LA, Li L, Amin AD, Pongtornpipat P, Zerio CJ, Ambrose AJ, Paine-Murrieta G, Greninger P, Vega F, Benes CH, Packham G, Rodríguez AD, Chapman E, Schatz JH. Peters TL, et al. Among authors: rodriguez ad. Clin Cancer Res. 2018 Sep 1;24(17):4256-4270. doi: 10.1158/1078-0432.CCR-17-3645. Epub 2018 May 29. Clin Cancer Res. 2018. PMID: 29844128 Free PMC article.
Searching for Small Molecules with an Atomic Sort.
Duggan BM, Cullum R, Fenical W, Amador LA, Rodríguez AD, La Clair JJ. Duggan BM, et al. Among authors: rodriguez ad. Angew Chem Int Ed Engl. 2020 Jan 13;59(3):1144-1148. doi: 10.1002/anie.201911862. Epub 2019 Dec 2. Angew Chem Int Ed Engl. 2020. PMID: 31696595 Free PMC article.
A comparative study of small molecules targeting eIF4A.
Naineni SK, Itoua Maïga R, Cencic R, Putnam AA, Amador LA, Rodriguez AD, Jankowsky E, Pelletier J. Naineni SK, et al. Among authors: rodriguez ad. RNA. 2020 May;26(5):541-549. doi: 10.1261/rna.072884.119. Epub 2020 Feb 3. RNA. 2020. PMID: 32014999 Free PMC article.
Corrigendum: Searching for Small Molecules with an Atomic Sort.
Duggan BM, Cullum R, Fenical W, Amador LA, Rodríguez AD, La Clair JJ. Duggan BM, et al. Among authors: rodriguez ad. Angew Chem Int Ed Engl. 2020 Mar 23;59(13):4993. doi: 10.1002/anie.202000826. Angew Chem Int Ed Engl. 2020. PMID: 32175689 No abstract available.
239 results