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Page 1
Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates.
Buckley M, Araínga M, Maiorino L, Pires IS, Kim BJ, Michaels KK, Dye J, Qureshi K, Zhang YJ, Mak H, Steichen JM, Schief WR, Villinger F, Irvine DJ. Buckley M, et al. Among authors: maiorino l. Mol Ther. 2025 Jan 10:S1525-0016(25)00012-7. doi: 10.1016/j.ymthe.2025.01.008. Online ahead of print. Mol Ther. 2025. PMID: 39797396 Free article.
Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle.
Yousefpour P, Zhang YJ, Maiorino L, Melo MB, Arainga Ramirez MA, Kumarapperuma SC, Xiao P, Silva M, Li N, Michaels KK, Georgeson E, Eskandarzadeh S, Kubitz M, Groschel B, Qureshi K, Fontenot J, Hangartner L, Nedellec R, Love JC, Burton DR, Schief WR, Villinger FJ, Irvine DJ. Yousefpour P, et al. Among authors: maiorino l. PNAS Nexus. 2024 Nov 25;3(12):pgae529. doi: 10.1093/pnasnexus/pgae529. eCollection 2024 Dec. PNAS Nexus. 2024. PMID: 39677368 Free PMC article.
Diverse priming outcomes under conditions of very rare precursor B cells.
Madden PJ, Marina-Zárate E, Rodrigues KA, Steichen JM, Shil M, Ni K, Michaels KK, Maiorino L, Upadhyay AA, Saha S, Pradhan A, Kalyuzhiny O, Liguori A, Lopez PG, Phung I, Phelps N, Georgeson E, Alavi N, Kubitz M, Lu D, Eskandarzadeh S, Metz A, Rodriguez OL, Shields K, Schultze S, Smith ML, Healy BS, Lim D, Lewis VR, Ben-Akiva E, Pinney W, Gregory J, Xiao S, Carnathan DG, Kasturi SP, Watson CT, Bosinger SE, Silvestri G, Schief WR, Irvine DJ, Crotty S. Madden PJ, et al. Among authors: maiorino l. bioRxiv [Preprint]. 2024 Nov 25:2024.11.21.624746. doi: 10.1101/2024.11.21.624746. bioRxiv. 2024. PMID: 39651117 Free PMC article. Preprint.
Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response.
Bhagchandani SH, Yang L, Lam JH, Maiorino L, Ben-Akiva E, Rodrigues KA, Romanov A, Suh H, Aung A, Wu S, Wadhera A, Chakraborty AK, Irvine DJ. Bhagchandani SH, et al. Among authors: maiorino l. Sci Immunol. 2024 Sep 20;9(99):eadl3755. doi: 10.1126/sciimmunol.adl3755. Epub 2024 Sep 20. Sci Immunol. 2024. PMID: 39303017 Free PMC article.
Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP.
Yousefpour P, Zhang YJ, Maiorino L, Melo MB, Arainga Ramirez MA, Kumarapperuma SC, Xiao P, Silva M, Li N, Michaels KK, Georgeson E, Eskandarzadeh S, Kubitz M, Groschel B, Qureshi K, Fontenot J, Hangartner L, Nedellec R, Love JC, Burton DR, Schief WR, Villinger FJ, Irvine DJ. Yousefpour P, et al. Among authors: maiorino l. bioRxiv [Preprint]. 2024 Aug 28:2024.08.28.608716. doi: 10.1101/2024.08.28.608716. bioRxiv. 2024. Update in: PNAS Nexus. 2024 Nov 25;3(12):pgae529. doi: 10.1093/pnasnexus/pgae529 PMID: 39253464 Free PMC article. Updated. Preprint.
Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion.
Rodrigues KA, Zhang YJ, Aung A, Morgan DM, Maiorino L, Yousefpour P, Gibson G, Ozorowski G, Gregory JR, Amlashi P, Buckley M, Ward AB, Schief WR, Love JC, Irvine DJ. Rodrigues KA, et al. Among authors: maiorino l. bioRxiv [Preprint]. 2024 Aug 19:2024.08.19.608655. doi: 10.1101/2024.08.19.608655. bioRxiv. 2024. PMID: 39229011 Free PMC article. Preprint.
Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant.
Ramezani-Rad P, Marina-Zárate E, Maiorino L, Myers A, Michaels KK, Pires IS, Bloom NI, Lopez PG, Cottrell CA, Burton I, Groschel B, Pradhan A, Stiegler G, Budai M, Kumar D, Pallerla S, Sayeed E, Sagar SL, Kasturi SP, Van Rompay KKA, Hangartner L, Wagner A, Burton DR, Schief WR, Crotty S, Irvine DJ. Ramezani-Rad P, et al. Among authors: maiorino l. bioRxiv [Preprint]. 2024 Aug 3:2024.07.31.604373. doi: 10.1101/2024.07.31.604373. bioRxiv. 2024. PMID: 39211109 Free PMC article. Preprint.
Cancer tissue of origin constrains the growth and metabolism of metastases.
Sivanand S, Gultekin Y, Winter PS, Vermeulen SY, Tchourine KM, Abbott KL, Danai LV, Gourgue F, Do BT, Crowder K, Kunchok T, Lau AN, Darnell AM, Jefferson A, Morita S, Duda DG, Aguirre AJ, Wolpin BM, Henning N, Spanoudaki V, Maiorino L, Irvine DJ, Yilmaz OH, Lewis CA, Vitkup D, Shalek AK, Vander Heiden MG. Sivanand S, et al. Among authors: maiorino l. Nat Metab. 2024 Sep;6(9):1668-1681. doi: 10.1038/s42255-024-01105-9. Epub 2024 Aug 19. Nat Metab. 2024. PMID: 39160333
Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity.
Santollani L, Maiorino L, Zhang YJ, Palmeri JR, Stinson JA, Duhamel LR, Qureshi K, Suggs JR, Porth OT, Pinney W 3rd, Msari RA, Walsh AA, Wittrup KD, Irvine DJ. Santollani L, et al. Among authors: maiorino l. Nat Immunol. 2024 Oct;25(10):1820-1829. doi: 10.1038/s41590-024-01925-7. Epub 2024 Aug 7. Nat Immunol. 2024. PMID: 39112631 Free PMC article.
86 results