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Structural determinants of ivabradine block of the open pore of HCN4.
Saponaro A, Krumbach JH, Chaves-Sanjuan A, Sharifzadeh AS, Porro A, Castelli R, Hamacher K, Bolognesi M, DiFrancesco D, Clarke OB, Thiel G, Moroni A. Saponaro A, et al. Among authors: sharifzadeh as. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2402259121. doi: 10.1073/pnas.2402259121. Epub 2024 Jun 25. Proc Natl Acad Sci U S A. 2024. PMID: 38917012 Free PMC article.
Gating movements and ion permeation in HCN4 pacemaker channels.
Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A. Saponaro A, et al. Among authors: sharifzadeh as. Mol Cell. 2021 Jul 15;81(14):2929-2943.e6. doi: 10.1016/j.molcel.2021.05.033. Epub 2021 Jun 23. Mol Cell. 2021. PMID: 34166608 Free PMC article.