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α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes.
Šneiderienė G, Czekalska MA, Xu CK, Jayaram AK, Krainer G, Arter WE, Peter QAE, Castellana-Cruz M, Saar KL, Levin A, Mueller T, Fiedler S, Devenish SRA, Fiegler H, Kumita JR, Knowles TPJ. Šneiderienė G, et al. Among authors: knowles tpj. ACS Nano. 2024 Jul 9;18(27):17469-17482. doi: 10.1021/acsnano.3c10889. Epub 2024 Jun 25. ACS Nano. 2024. PMID: 38916260 Free PMC article.
Population of nonnative states of lysozyme variants drives amyloid fibril formation.
Buell AK, Dhulesia A, Mossuto MF, Cremades N, Kumita JR, Dumoulin M, Welland ME, Knowles TPJ, Salvatella X, Dobson CM. Buell AK, et al. Among authors: knowles tpj. J Am Chem Soc. 2011 May 25;133(20):7737-7743. doi: 10.1021/ja109620d. Epub 2011 Apr 29. J Am Chem Soc. 2011. PMID: 21528861 Free PMC article.
Fluctuations in the Kinetics of Linear Protein Self-Assembly.
Michaels TC, Dear AJ, Kirkegaard JB, Saar KL, Weitz DA, Knowles TP. Michaels TC, et al. Phys Rev Lett. 2016 Jun 24;116(25):258103. doi: 10.1103/PhysRevLett.116.258103. Epub 2016 Jun 21. Phys Rev Lett. 2016. PMID: 27391756
Dynamic microfluidic control of supramolecular peptide self-assembly.
Arnon ZA, Vitalis A, Levin A, Michaels TCT, Caflisch A, Knowles TPJ, Adler-Abramovich L, Gazit E. Arnon ZA, et al. Among authors: knowles tpj. Nat Commun. 2016 Oct 25;7:13190. doi: 10.1038/ncomms13190. Nat Commun. 2016. PMID: 27779182 Free PMC article.
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.
Habchi J, Chia S, Limbocker R, Mannini B, Ahn M, Perni M, Hansson O, Arosio P, Kumita JR, Challa PK, Cohen SI, Linse S, Dobson CM, Knowles TP, Vendruscolo M. Habchi J, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208. doi: 10.1073/pnas.1615613114. Epub 2016 Dec 23. Proc Natl Acad Sci U S A. 2017. PMID: 28011763 Free PMC article.
417 results