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Synthetic genomes unveil the effects of synonymous recoding.
Nyerges A, Chiappino-Pepe A, Budnik B, Baas-Thomas M, Flynn R, Yan S, Ostrov N, Liu M, Wang M, Zheng Q, Hu F, Chen K, Rudolph A, Chen D, Ahn J, Spencer O, Ayalavarapu V, Tarver A, Harmon-Smith M, Hamilton M, Blaby I, Yoshikuni Y, Hajian B, Jin A, Kintses B, Szamel M, Seregi V, Shen Y, Li Z, Church GM. Nyerges A, et al. Among authors: ostrov n. bioRxiv [Preprint]. 2024 Jun 16:2024.06.16.599206. doi: 10.1101/2024.06.16.599206. bioRxiv. 2024. PMID: 38915524 Free PMC article. Preprint.
Technological challenges and milestones for writing genomes.
Ostrov N, Beal J, Ellis T, Gordon DB, Karas BJ, Lee HH, Lenaghan SC, Schloss JA, Stracquadanio G, Trefzer A, Bader JS, Church GM, Coelho CM, Efcavitch JW, Güell M, Mitchell LA, Nielsen AAK, Peck B, Smith AC, Stewart CN Jr, Tekotte H. Ostrov N, et al. Science. 2019 Oct 18;366(6463):310-312. doi: 10.1126/science.aay0339. Science. 2019. PMID: 31624201 Free article. No abstract available.
Establishing a Cell-Free Vibrio natriegens Expression System.
Wiegand DJ, Lee HH, Ostrov N, Church GM. Wiegand DJ, et al. Among authors: ostrov n. ACS Synth Biol. 2018 Oct 19;7(10):2475-2479. doi: 10.1021/acssynbio.8b00222. Epub 2018 Sep 12. ACS Synth Biol. 2018. PMID: 30160938
Design, synthesis, and testing toward a 57-codon genome.
Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, Tyree G, Gonzales A, Wanner BL, Norville JE, Lajoie MJ, Church GM. Ostrov N, et al. Science. 2016 Aug 19;353(6301):819-22. doi: 10.1126/science.aaf3639. Science. 2016. PMID: 27540174
13 results