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Caspase Inhibition Restores Collagen I α1 and Fibronectin Release in Cigarette Smoke Extract-Exposed Human Lung Fibroblasts.
La Mensa A, Buscetta M, Woldhuis RR, Cimino M, Giuffrè MR, Cristaldi M, Dino P, Fiore L, Fucarino A, Lo Iacono G, Bertani A, Brandsma CA, Bucchieri F, Cipollina C. La Mensa A, et al. Among authors: woldhuis rr. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 8. doi: 10.1152/ajplung.00214.2024. Online ahead of print. Am J Physiol Lung Cell Mol Physiol. 2025. PMID: 39772929
Highlights from the 11th Bronchitis International Symposium: "Heterogeneity of Lung Disease in a Changing Environment," Groningen, The Netherlands, 2024.
Pouwels SD, Ter Haar EAMD, Heijink IH, Hylkema MN, Koster TD, Kuks PJM, Maassen S, Slebos DJ, Vasse GF, de Vries M, Woldhuis RR, Brandsma CA. Pouwels SD, et al. Among authors: woldhuis rr. Respiration. 2024;103(12):765-776. doi: 10.1159/000541655. Epub 2024 Sep 30. Respiration. 2024. PMID: 39348815 Free article.
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease.
Joglekar MM, Bekker NJ, Koloko Ngassie ML, Vonk JM, Borghuis T, Reinders-Luinge M, Bakker J, Woldhuis RR, Pouwels SD, Melgert BN, Timens W, Brandsma CA, Burgess JK. Joglekar MM, et al. Among authors: woldhuis rr. Am J Physiol Lung Cell Mol Physiol. 2024 Sep 1;327(3):L304-L318. doi: 10.1152/ajplung.00332.2023. Epub 2024 Jun 25. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38915286
A proteomics approach to identify COPD-related changes in lung fibroblasts.
Bekker NJ, van Pijkeren A, Wolters JC, Sánchez Brotons A, Guryev V, Woldhuis RR, Bischoff R, Alkema W, Horvatovich P, van Nijnatten JLL, van den Berge M, Timens W, Brandsma CA. Bekker NJ, et al. Among authors: woldhuis rr. Am J Physiol Lung Cell Mol Physiol. 2023 Apr 1;324(4):L521-L535. doi: 10.1152/ajplung.00105.2022. Epub 2023 Feb 21. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36808722 Free article.
BET proteins are associated with the induction of small airway fibrosis in COPD.
Zakarya R, Chan YL, Rutting S, Reddy K, Bozier J, Woldhuis RR, Xenaki D, Van Ly D, Chen H, Brandsma CA, Adcock IM, Oliver BG. Zakarya R, et al. Among authors: woldhuis rr. Thorax. 2021 Jul;76(7):647-655. doi: 10.1136/thoraxjnl-2020-215092. Epub 2021 Jan 27. Thorax. 2021. PMID: 33504568
Link between increased cellular senescence and extracellular matrix changes in COPD.
Woldhuis RR, de Vries M, Timens W, van den Berge M, Demaria M, Oliver BGG, Heijink IH, Brandsma CA. Woldhuis RR, et al. Am J Physiol Lung Cell Mol Physiol. 2020 Jul 1;319(1):L48-L60. doi: 10.1152/ajplung.00028.2020. Epub 2020 May 27. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32460521 Free article.
Age-related gene and miRNA expression changes in airways of healthy individuals.
Ong J, Woldhuis RR, Boudewijn IM, van den Berg A, Kluiver J, Kok K, Terpstra MM, Guryev V, de Vries M, Vermeulen CJ, Timens W, van den Berge M, Brandsma CA. Ong J, et al. Among authors: woldhuis rr. Sci Rep. 2019 Mar 6;9(1):3765. doi: 10.1038/s41598-019-39873-0. Sci Rep. 2019. PMID: 30842487 Free PMC article.
Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
Brandsma CA, de Vries M, Costa R, Woldhuis RR, Königshoff M, Timens W. Brandsma CA, et al. Among authors: woldhuis rr. Eur Respir Rev. 2017 Dec 6;26(146):170073. doi: 10.1183/16000617.0073-2017. Print 2017 Dec 31. Eur Respir Rev. 2017. PMID: 29212834 Free PMC article. Review.
11 results