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Coronary CT angiography-guided management of patients with stable chest pain: 10-year outcomes from the SCOT-HEART randomised controlled trial in Scotland.
Williams MC, Wereski R, Tuck C, Adamson PD, Shah ASV, van Beek EJR, Roditi G, Berry C, Boon N, Flather M, Lewis S, Norrie J, Timmis AD, Mills NL, Dweck MR, Newby DE; SCOT-HEART Investigators. Williams MC, et al. Lancet. 2025 Jan 25;405(10475):329-337. doi: 10.1016/S0140-6736(24)02679-5. Lancet. 2025. PMID: 39863372 Free article. Clinical Trial.
Enzymatic Cascades for Stereoselective and Regioselective Amide Bond Assembly.
Torri D, Bering L, Yates LRL, Angiolini SM, Xu G, Cuesta-Hoyos S, Shepherd SA, Micklefield J. Torri D, et al. Among authors: shepherd sa. Angew Chem Int Ed Engl. 2025 Jan 10:e202422185. doi: 10.1002/anie.202422185. Online ahead of print. Angew Chem Int Ed Engl. 2025. PMID: 39792621
Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal.
Fernández-Sanromán Á, Fendler A, Tan BJY, Cattin AL, Spencer C, Thompson R, Au L, Lobon I, Pallikonda HA, Martin A, Byrne F, Franz A, Mikolajczak A, Rahman H, Tippu Z, Shepherd STC, Feng H, Deng D, Rowan A, Pickering L, Furness AJS, Young K, Nicol D, Rudman SM, O'Brien T, Edmonds K, Chandra A, Hazell S, Litchfield K, Kassiotis G, Larkin J, Turajlic S. Fernández-Sanromán Á, et al. Among authors: shepherd stc. Cancer Discov. 2025 Jan 9:OF1-OF23. doi: 10.1158/2159-8290.CD-24-0499. Online ahead of print. Cancer Discov. 2025. PMID: 39784160
Tracking non-genetic evolution from primary to metastatic ccRCC: TRACERx Renal.
Fernández-Sanromán Á, Fendler A, Tan BJY, Cattin AL, Spencer C, Thompson R, Au L, Lobon I, Pallikonda HA, Martin A, Byrne F, Franz A, Mikolajczak A, Rahman H, Tippu Z, Shepherd STC, Feng H, Deng D, Rowan A, Pickering L, Furness AJS, Young K, Nicol D, Rudman SM, O'Brien T, Edmonds K, Chandra A, Hazell S, Litchfield K, Kassiotis G, Larkin J, Turajlic S. Fernández-Sanromán Á, et al. Among authors: shepherd stc. Cancer Discov. 2025 Jan 8. doi: 10.1158/2159-8290.CD-24-0499. Online ahead of print. Cancer Discov. 2025. PMID: 39774619
Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery.
Padilla M, Shepherd SJ, Hanna AR, Kurnik M, Zhang X, Chen M, Byrnes J, Yamagata H, Ricciardi A, Joseph R, Mrksich K, Issadore D, Gupta K, Mitchell M. Padilla M, et al. Among authors: shepherd sj. bioRxiv [Preprint]. 2025 Jan 27:2024.12.19.629496. doi: 10.1101/2024.12.19.629496. bioRxiv. 2025. PMID: 39763759 Free PMC article. Preprint.
Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors.
Eadsforth TC, Torrie LS, Rowland P, Edgar EV, MacLean LM, Paterson C, Robinson DA, Shepherd SM, Thomas J, Thomas MG, Gray DW, Postis VLG, De Rycker M. Eadsforth TC, et al. Among authors: shepherd sm. J Biol Chem. 2024 Dec 9;301(1):108049. doi: 10.1016/j.jbc.2024.108049. Online ahead of print. J Biol Chem. 2024. PMID: 39638245 Free PMC article.
Early childhood body mass index growth and school readiness: A longitudinal cohort study.
Li X, Kahane A, Keown-Stoneman CDG, Omand JA, Borkhoff CM, Lebovic G, Maguire JL, Mamdani M, Parkin PC, Simpson JR, Tremblay MS, Vanderloo LM, Duku E, Reid-Westoby C, Janus M, Birken CS; TARGet Kids! Collaboration. Li X, et al. Paediatr Perinat Epidemiol. 2024 Nov;38(8):733-744. doi: 10.1111/ppe.13114. Paediatr Perinat Epidemiol. 2024. PMID: 39607066
954 results