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Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance.
Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K, Morimoto D, Yamaguchi L, Arai N, Matsumura R, Kawakami T, Mishima Y, Hojo H, Shimamura S, Ishikawa F, Tajima S, Tanaka K, Ariyoshi M, Shirakawa M, Ikeguchi M, Kidera A, Suetake I, Arita K, Nakanishi M. Ishiyama S, et al. Among authors: nishiyama a. Mol Cell. 2017 Oct 19;68(2):350-360.e7. doi: 10.1016/j.molcel.2017.09.037. Mol Cell. 2017. PMID: 29053958 Free article.
Enhanced processivity of Dnmt1 by monoubiquitinated histone H3.
Mishima Y, Brueckner L, Takahashi S, Kawakami T, Otani J, Shinohara A, Takeshita K, Garvilles RG, Watanabe M, Sakai N, Takeshima H, Nachtegael C, Nishiyama A, Nakanishi M, Arita K, Nakashima K, Hojo H, Suetake I. Mishima Y, et al. Among authors: nishiyama a. Genes Cells. 2020 Jan;25(1):22-32. doi: 10.1111/gtc.12732. Epub 2019 Dec 3. Genes Cells. 2020. PMID: 31680384 Free article.
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Nishiyama A, Mulholland CB, Bultmann S, Kori S, Endo A, Saeki Y, Qin W, Trummer C, Chiba Y, Yokoyama H, Kumamoto S, Kawakami T, Hojo H, Nagae G, Aburatani H, Tanaka K, Arita K, Leonhardt H, Nakanishi M. Nishiyama A, et al. Nat Commun. 2020 Mar 6;11(1):1222. doi: 10.1038/s41467-020-15006-4. Nat Commun. 2020. PMID: 32144273 Free PMC article.
Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.
Omori S, Wang TW, Johmura Y, Kanai T, Nakano Y, Kido T, Susaki EA, Nakajima T, Shichino S, Ueha S, Ozawa M, Yokote K, Kumamoto S, Nishiyama A, Sakamoto T, Yamaguchi K, Hatakeyama S, Shimizu E, Katayama K, Yamada Y, Yamazaki S, Iwasaki K, Miyoshi C, Funato H, Yanagisawa M, Ueno H, Imoto S, Furukawa Y, Yoshida N, Matsushima K, Ueda HR, Miyajima A, Nakanishi M. Omori S, et al. Among authors: nishiyama a. Cell Metab. 2020 Nov 3;32(5):814-828.e6. doi: 10.1016/j.cmet.2020.09.006. Epub 2020 Sep 18. Cell Metab. 2020. PMID: 32949498 Free article.
1,257 results