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Page 1
KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME. Sigafoos AN, et al. Among authors: raja arul gl. Cancer Res Commun. 2024 Jul 1;4(7):1677-1689. doi: 10.1158/2767-9764.CRC-23-0464. Cancer Res Commun. 2024. PMID: 38896052 Free PMC article.
SUFU promotes GLI activity in a Hedgehog-independent manner in pancreatic cancer.
Paradise BD, Gainullin VG, Almada LL, Sigafoos AN, Sen S, Vera RE, Raja Arul GL, Toruner M, Pease DR, Gonzalez AL, Mentucci FM, Grasso DH, Fernandez-Zapico ME. Paradise BD, et al. Among authors: raja arul gl. Biochem J. 2023 Aug 16;480(15):1199-1216. doi: 10.1042/BCJ20220439. Biochem J. 2023. PMID: 37477952
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1.
Almada LL, Barroso K, Sen S, Toruner M, Sigafoos AN, Raja Arul GL, Pease DR, Vera RE, Olson RLO, Auner HW, Pedeux R, Iovanna JL, Chevet E, Fernandez-Zapico ME. Almada LL, et al. Among authors: raja arul gl. Biochim Biophys Acta Gene Regul Mech. 2023 Jun;1866(2):194924. doi: 10.1016/j.bbagrm.2023.194924. Epub 2023 Feb 25. Biochim Biophys Acta Gene Regul Mech. 2023. PMID: 36842643 Free article.