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The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity.
Marchitto L, Richard J, Prévost J, Tauzin A, Yang D, Chiu T, Chen HC, Díaz-Salinas MA, Nayrac M, Benlarbi M, Beaudoin-Bussières G, Anand SP, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Bourassa C, Tolbert WD, Hahn BH, Munro JB, Pazgier M, Smith AB 3rd, Finzi A. Marchitto L, et al. Among authors: nayrac m. bioRxiv [Preprint]. 2024 Jun 7:2024.06.07.597978. doi: 10.1101/2024.06.07.597978. bioRxiv. 2024. Update in: J Virol. 2024 Oct 22;98(10):e0101624. doi: 10.1128/jvi.01016-24 PMID: 38895270 Free PMC article. Updated. Preprint.
Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction.
Bunet R, Nayrac M, Ramani H, Sylla M, Durand M, Chartrand-Lefebvre C, Routy JP, Landay AL, Gauchat JF, Chomont N, Ancuta P, Kaufmann DE, Bernard N, Tremblay CL, El-Far M. Bunet R, et al. Among authors: nayrac m. Front Immunol. 2021 May 27;12:673061. doi: 10.3389/fimmu.2021.673061. eCollection 2021. Front Immunol. 2021. PMID: 34122431 Free PMC article.
Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells.
Dubé M, Tastet O, Dufour C, Sannier G, Brassard N, Delgado GG, Pagliuzza A, Richard C, Nayrac M, Routy JP, Prat A, Estes JD, Fromentin R, Chomont N, Kaufmann DE. Dubé M, et al. Among authors: nayrac m. Cell Host Microbe. 2023 Sep 13;31(9):1507-1522.e5. doi: 10.1016/j.chom.2023.08.006. Cell Host Microbe. 2023. PMID: 37708853 Free PMC article.
Hepatitis E virus replication in human intestinal cells.
Marion O, Lhomme S, Nayrac M, Dubois M, Pucelle M, Requena M, Migueres M, Abravanel F, Peron JM, Carrere N, Suc B, Delobel P, Kamar N, Izopet J. Marion O, et al. Among authors: nayrac m. Gut. 2020 May;69(5):901-910. doi: 10.1136/gutjnl-2019-319004. Epub 2019 Nov 14. Gut. 2020. PMID: 31727684
Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset.
Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed H, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann DE, Finzi A. Anand SP, et al. Among authors: nayrac m. bioRxiv [Preprint]. 2021 Jan 25:2021.01.25.428097. doi: 10.1101/2021.01.25.428097. bioRxiv. 2021. Update in: Cell Rep Med. 2021 Jun 15;2(6):100290. doi: 10.1016/j.xcrm.2021.100290 PMID: 33532774 Free PMC article. Updated. Preprint.
A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: nayrac m. bioRxiv [Preprint]. 2021 Mar 18:2021.03.18.435972. doi: 10.1101/2021.03.18.435972. bioRxiv. 2021. PMID: 33758857 Free PMC article. Preprint.
Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset.
Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed H, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann DE, Finzi A. Anand SP, et al. Among authors: nayrac m. Cell Rep Med. 2021 Jun 15;2(6):100290. doi: 10.1016/j.xcrm.2021.100290. Epub 2021 May 5. Cell Rep Med. 2021. PMID: 33969322 Free PMC article.
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: nayrac m. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. Cell Host Microbe. 2021. PMID: 34133950 Free PMC article.
28 results