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Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding.
Liang J, Lambrecht MJ, Arenzana TL, Aubert-Nicol S, Bao L, Broccatelli F, Cai J, Eidenschenk C, Everett C, Garner T, Gruber F, Haghshenas P, Huestis MP, Hsu PL, Kou P, Jakalian A, Larouche-Gauthier R, Leclerc JP, Leung DH, Martin A, Murray J, Prangley M, Rutz S, Kakiuchi-Kiyota S, Satz AL, Skelton NJ, Steffek M, Stoffler D, Sudhamsu J, Tan S, Wang J, Wang S, Wang Q, Wendorff TJ, Wichert M, Yadav A, Yu C, Wang X. Liang J, et al. Among authors: yadav a. ACS Med Chem Lett. 2024 May 29;15(6):864-872. doi: 10.1021/acsmedchemlett.4c00068. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894924
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).
Zeng M, Grandner JM, Bryan MC, Verma V, Larouche-Gauthier R, Leclerc JP, Zhao L, Haghshenas P, Aubert-Nicol S, Yadav A, Ashley M, Chen JZ, Durk M, Samy KE, Nespi M, Levy E, Merrick K, Moffat JG, Murray J, Oh A, Orr C, Segal E, Sims J, Sneeringer C, Prangley M, Vartanian S, Magnuson S, Parr BT. Zeng M, et al. Among authors: yadav a. ACS Med Chem Lett. 2023 Aug 24;14(9):1179-1187. doi: 10.1021/acsmedchemlett.3c00142. eCollection 2023 Sep 14. ACS Med Chem Lett. 2023. PMID: 37736184 Free PMC article.
Nickel-Catalyzed N-Arylation of Fluoroalkylamines.
McGuire RT, Yadav AA, Stradiotto M. McGuire RT, et al. Among authors: yadav aa. Angew Chem Int Ed Engl. 2021 Feb 19;60(8):4080-4084. doi: 10.1002/anie.202014340. Epub 2020 Dec 23. Angew Chem Int Ed Engl. 2021. PMID: 33201556
Information sharing within a social network is key to behavioral flexibility-Lessons from mice tested under seminaturalistic conditions.
Winiarski M, Madecka A, Yadav A, Borowska J, Wołyniak MR, Jędrzejewska-Szmek J, Kondrakiewicz L, Mankiewicz L, Chaturvedi M, Wójcik DK, Turzyński K, Puścian A, Knapska E. Winiarski M, et al. Among authors: yadav a. Sci Adv. 2025 Jan 3;11(1):eadm7255. doi: 10.1126/sciadv.adm7255. Epub 2025 Jan 3. Sci Adv. 2025. PMID: 39752499 Free PMC article.
3,471 results