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EGFRvIII Confers Sensitivity to Saracatinib in a STAT5-Dependent Manner in Glioblastoma.
Blomquist MR, Eghlimi R, Beniwal A, Grief D, Nascari DG, Inge L, Sereduk CP, Tuncali S, Roos A, Inforzato H, Sharma R, Pirrotte P, Mehta S, Fortin Ensign SP, Loftus JC, Tran NL. Blomquist MR, et al. Among authors: tran nl. Int J Mol Sci. 2024 Jun 6;25(11):6279. doi: 10.3390/ijms25116279. Int J Mol Sci. 2024. PMID: 38892466 Free PMC article.
EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.
Roos A, Dhruv HD, Peng S, Inge LJ, Tuncali S, Pineda M, Millard N, Mayo Z, Eschbacher JM, Loftus JC, Winkles JA, Tran NL. Roos A, et al. Among authors: tran nl. Mol Cancer Res. 2018 Jul;16(7):1185-1195. doi: 10.1158/1541-7786.MCR-18-0125. Epub 2018 May 3. Mol Cancer Res. 2018. PMID: 29724813 Free PMC article.
The Pyk2 FERM domain as a target to inhibit glioma migration.
Loftus JC, Yang Z, Tran NL, Kloss J, Viso C, Berens ME, Lipinski CA. Loftus JC, et al. Among authors: tran nl. Mol Cancer Ther. 2009 Jun;8(6):1505-14. doi: 10.1158/1535-7163.MCT-08-1055. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509258 Free PMC article.
TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance.
Loftus JC, Dhruv H, Tuncali S, Kloss J, Yang Z, Schumacher CA, Cao B, Williams BO, Eschbacher JM, Ross JT, Tran NL. Loftus JC, et al. Among authors: tran nl. Mol Cancer Res. 2013 Aug;11(8):865-74. doi: 10.1158/1541-7786.MCR-13-0008. Epub 2013 May 22. Mol Cancer Res. 2013. PMID: 23699535 Free PMC article.
The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasion via tumor necrosis factor receptor-associated factor 2.
Fortin Ensign SP, Mathews IT, Eschbacher JM, Loftus JC, Symons MH, Tran NL. Fortin Ensign SP, et al. Among authors: tran nl. J Biol Chem. 2013 Jul 26;288(30):21887-97. doi: 10.1074/jbc.M113.468686. Epub 2013 Jun 17. J Biol Chem. 2013. PMID: 23775076 Free PMC article.
220 results