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Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Cellupica E, Gaiassi A, Rocchio I, Rovelli G, Pomarico R, Sandrone G, Caprini G, Cordella P, Cukier C, Fossati G, Marchini M, Bebel A, Airoldi C, Palmioli A, Stevenazzi A, Steinkühler C, Vergani B. Cellupica E, et al. Among authors: marchini m. Int J Mol Sci. 2024 May 28;25(11):5885. doi: 10.3390/ijms25115885. Int J Mol Sci. 2024. PMID: 38892072 Free PMC article.
Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation.
Vergani B, Sandrone G, Marchini M, Ripamonti C, Cellupica E, Galbiati E, Caprini G, Pavich G, Porro G, Rocchio I, Lattanzio M, Pezzuto M, Skorupska M, Cordella P, Pagani P, Pozzi P, Pomarico R, Modena D, Leoni F, Perego R, Fossati G, Steinkühler C, Stevenazzi A. Vergani B, et al. Among authors: marchini m. J Med Chem. 2019 Dec 12;62(23):10711-10739. doi: 10.1021/acs.jmedchem.9b01194. Epub 2019 Nov 25. J Med Chem. 2019. PMID: 31710483
Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity.
Cellupica E, Caprini G, Cordella P, Cukier C, Fossati G, Marchini M, Rocchio I, Sandrone G, Vanoni MA, Vergani B, Źrubek K, Stevenazzi A, Steinkühler C. Cellupica E, et al. Among authors: marchini m. J Biol Chem. 2023 Jan;299(1):102800. doi: 10.1016/j.jbc.2022.102800. Epub 2022 Dec 15. J Biol Chem. 2023. PMID: 36528061 Free PMC article.
Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.
Mingozzi M, Dal Corso A, Marchini M, Guzzetti I, Civera M, Piarulli U, Arosio D, Belvisi L, Potenza D, Pignataro L, Gennari C. Mingozzi M, et al. Among authors: marchini m. Chemistry. 2013 Mar 11;19(11):3563-7. doi: 10.1002/chem.201204639. Epub 2013 Feb 19. Chemistry. 2013. PMID: 23424096 No abstract available.
241 results