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Page 1
Chemogenomics for NR1 nuclear hormone receptors.
Isigkeit L, Schallmayer E, Busch R, Brunello L, Menge A, Elson L, Müller S, Knapp S, Stolz A, Marschner JA, Merk D. Isigkeit L, et al. Among authors: merk d. Nat Commun. 2024 Jun 18;15(1):5201. doi: 10.1038/s41467-024-49493-6. Nat Commun. 2024. PMID: 38890295 Free PMC article.
Development of Nuclear Receptor Modulators.
Schierle S, Merk D. Schierle S, et al. Among authors: merk d. Methods Mol Biol. 2018;1824:245-260. doi: 10.1007/978-1-4939-8630-9_14. Methods Mol Biol. 2018. PMID: 30039411
Molecular tuning of farnesoid X receptor partial agonism.
Merk D, Sreeramulu S, Kudlinzki D, Saxena K, Linhard V, Gande SL, Hiller F, Lamers C, Nilsson E, Aagaard A, Wissler L, Dekker N, Bamberg K, Schubert-Zsilavecz M, Schwalbe H. Merk D, et al. Nat Commun. 2019 Jul 2;10(1):2915. doi: 10.1038/s41467-019-10853-2. Nat Commun. 2019. PMID: 31266946 Free PMC article.
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.
Gellrich L, Heitel P, Heering J, Kilu W, Pollinger J, Goebel T, Kahnt A, Arifi S, Pogoda W, Paulke A, Steinhilber D, Proschak E, Wurglics M, Schubert-Zsilavecz M, Chaikuad A, Knapp S, Bischoff I, Fürst R, Merk D. Gellrich L, et al. Among authors: merk d. J Med Chem. 2020 Jul 9;63(13):6727-6740. doi: 10.1021/acs.jmedchem.9b02150. Epub 2020 Jun 4. J Med Chem. 2020. PMID: 32356658
Design and Structural Optimization of Dual FXR/PPARδ Activators.
Schierle S, Neumann S, Heitel P, Willems S, Kaiser A, Pollinger J, Merk D. Schierle S, et al. Among authors: merk d. J Med Chem. 2020 Aug 13;63(15):8369-8379. doi: 10.1021/acs.jmedchem.0c00618. Epub 2020 Jul 20. J Med Chem. 2020. PMID: 32687365
195 results